Radiological Study of Cartilage Graft in Repair of Experimentally Radial Bone Defect in Rabbit
Subject Areas : Journal of Large Animal Clinical Science Research(JLACSR)
Keywords: Radiography, Radius bone, Cartilage, Bone Graft,
Abstract :
Sixteen adult male New Zealand white rabbits having body weight ranged from 3.0-3.5 Kg. Under general anesthesia, a segmental full thickness bone defect of 1 cm in length was created in the middle of the right radial shaft in all rabbits. They were divided into two groups of 8 rabbits each. Group I was considered as control and the fractured site was fixed using finger bone plate with 4 screws, whereas the ear cartilage of 1.1 cm graft was used to fill the gap after fracture fixation in Group II. Radiography was done before and after creating defects and on 15, 30 and 60 days to evaluate local reaction as callus formation are concerned. On the radiographs during the whole process, bone repair in Group I was not as perfect as those in Group II samples and trace of internal callus filled the gap incompletely in 60 days in Group I, whereas in Group II internal callus almost was formed on 30 days and in addition intercortical callus was seen supporting to cover and filled the gap completely in this group.Cartilage graft is suitable alternative bone filler and radiography is reliable techniques to trace local reaction at proper time.
1- Bauer, T. W., Muschler, G. F., (2000): Bone graft materials. Clinical Orthopedy. 371: 10-27.
2- Bronner, F., Farach-Carson, M. C., Rodan, G. A., (2003): Bone Formation (Topics in Bone Biology). Springer. 1st Edition:3-50.
3- Cotti E.,Campisi, G., (2004): Advanced radiographic techniques for the detection of lesions in bone. Endod Topics. 7:52-72
4- Fleknell. P., (2009): Laboratory Animal Anesthesia . 3th edition, WB Saunders Co. Philadelphia, Elsvier Inc:281.
5- Fossum, T. W., (2007) : Small Animals Surgery. 3rd ed. st louis: Mosby Publication: 821.
6- Graf, M. V., Stahl-Kent, T., Ben-Ami, S., Strauss, A., Yand, A., Itzchak, Y., (2008): Radigraphic and Sonographic detection of occult bone fractures. Pediatries Radiology. 18: 383-385.
7- Haktanir, A., Uysal, O. A and Yildiz, L., (2005): Radiologic and histologic assessment of diced cartilage graft for cranial bone defects of rabbits: An experimental study. Aesthesia Plastice Surgery. 29: 195-201.
8- Hasenwinkel, J., (2004): Encyclopedia of Biomaterials and Biomedical engineering: 170-179.
9- Henry, G. A., (2007): Fracture Healing and Complications. In: Textbook of Veterinary Diagnostic Radiology, Thrall, D. E. 5th ed. WB Saunders Co. Philadelphia: 284-304.
10- Mahl, C. R. W., Fontanella, V., (2008): Evaluation by digital subtraction radiography of induced changes in the bone density of the female rat mandible. Dentomaxillofac Radiol. 37:438-44.
11- Miranda, E. S., Cradoso, F. T. S., Filho, J. F. M., Barreto, M. R., Teixeira, R. M., Wanderley, A. L., Fernandes, K. E., (2005): Organic and inorganic bone graft use in Rabbit ’s radius surgical fractures repair: An exprimental and comparative study. Acta Orthopedy Brazil. 13, 5:245-248.
12- Piermattei, D. L., (2000) Small animal Orthopedics and Fracture Repair. WB Saunders Co. Philadelphia: 81.
13- Rahimzadeh, R., Veshkini, A., Sharifi, D., Hesaraki, S., (2012): Value of color Doppler ultrasonography and radiography for the assessment of the cancellous bone scaffold coated with nano-hydroxyapatite in repair of radial bone in rabbit. Acta Cirúrgica Brasileira . 27, 2:148-154.
14- Saikku-Backstrom, A., Raiha, J. E., Valimaa, T et al., (2005): Repair of radial fractures in toy breed dogs with self-reinforced biodegradable bone plates, metal screws, and light-weight external coaptation. Veterinary. Surgery. 34:11.
_||_