Assessment of hematological parameters and some biochemical parameters in dogs infected with parvovirus

Subject Areas : Journal of Large Animal Clinical Science Research(JLACSR)

Boshra sadat Bani hashemi ¹ (Department of Clinical Pathology, Faculty of Veterinary Medicine, Babol Branch, Islamic Azad University, Babol, Iran)
abbas kalantari ² (Department of Clinical Pathology, Faculty of Veterinary Medicine, Babol Branch, Islamic Azad University, Babol, Iran)

Received: 2023-11-09 Accepted : 2024-01-08 Published : 2023-11-22

Keywords: Dog, canine parvovirus, , hematological parameters, , biochemical parameters, , , ,

Abstract :

Parvovirus in dogs causes a fatal disease with the effects of destruction of hematopoietic precursor cells and involvement of various organs and parts such as intestinal epithelial cells, thymus and lymph nodes. To conduct this research sampling was done of 25 dogs with symptoms of gastroenteritis wich were positive with rapid test for canine parvovirus detection. After taking blood samples, the hematological and biochemical factors of serum were analyzed using statistical methods (Shapiro-Wilk and t-test) in comparison with reference values. The obtained results showed that the number of red and white blood cells, the number of neutrophils and lymphocytes, the concentration of hemoglobin and the percentage of hematocrit in dogs infected with parvovirus were significantly lower than the reference values (P<0.001). Also, the activities of aspartate aminotransferase (AST) and alkaline phosphatase (ALP) enzymes, blood urea nitrogen and serum creatinine of infected dogs were significantly higher than the reference values (P<0.001).the results of this study indicated the destructive effect of parvovirus on the desired indicators, and knowing the status of the blood panel can be of great help for the correct treatment of the disease.