Physiological and behavioral effects of feeding of Argas reflexus larvae in laboratory mice

Subject Areas :

Farid Rezaei ¹ , Maryam Maryam Karimi-Dehkord ² , Forogh Khavaran ³

1 - Department of Pathobiology, Faculty of Veterinary Medicine, Razi University, Kermanshah, Iran
2 - Department of clinical Sciences, Faculty of Veterinary Medicine, Shahrekord Branch, Islamic Azad University, Shahrekord, Iran
3 - MSc graduet of Biology, Islamic Azad University, hamedan branch

Received: 2021-04-13 Accepted : 2021-10-07 Published : 2021-09-23

Keywords: Mice, Argas reflexus, Physiologic, Larvae,

Abstract :

Inroduction & Objective: Argas reflexus or pigeon tick is a soft tick of Argas genus. This tick is an external parasite of poultry that often feeds on pigeon blood and is one of the most important pigeon ectoparasites that can endanger human health. The aim of this study was to investigate the physiological and behavioral effects of feeding Argas reflexus larvae on mice. Material and Method: After collecting the Argas reflexus ticks and in vitro production of their larvae, mice were infected with 30, 40 and 50 larvae in three treatments, respectively, and 5 mice were treated in each treatment. Then, Physiological symptoms such as changes in weight and temperature, behavioral changes and skin symptoms were monitored and recorded daily. Results: The results of this study show with increasing the number of larvae in infected mice, the severity of symptoms also increase. It also seems that in addition to the number of larvae, the longer feeding of larvae from the body of laboratory animals, the greater the severity of clinical and cutaneous symptoms and their stability. Conclusion: According to the results, it is necessary to pay attention to the dangers of the presence of this tick in birds as the main host of this tick and also in the habitat of humans and to develop control and preventive programs against this tick.

References:

 

1.Alipour-Tehranyو Y., Laffitte, E. (2018). Argas reflexus dermatitis and nocturnal pruritus. IDCases, 14; e00456. 1-2/

2.Almazán, C., Bonnet, S., Cote, M., Slovák, M., Park, Y., Šimo, L. (2018). A versatile model of hard tick infestation on lLaboratory rabbits. Journal of Visualized Experiments, 140; 1-7.

3.Bonnet. S., Liu, X. (2012). Laboratory artificial infection of hard ticks: a tool for the analysis of tick-borne pathogen transmission. Acarologia, 52(4); 453-464.

4.Dautelو H., Knülle, W. (1998). Seasonal oviposition and temperature requirements of eggs may limit northern distribution of European Argas reflexus (Acari: Argasidae). Journal of Medical Entomology, 35(1); 26-37.

5.Estrada-Peña, A., Jongejan, F. (1999). Ticks feeding on humans: a review of records on human-biting Ixodoidea with special reference to pathogen transmission. Experimental and applied acarology, 23(9);685-715.

6.Fisher, E. J., Mo, J., Lucky, A.W. (2006). Multiple pruritic papules from lone star tick larvae bites. Archives of Dermatology, (4); 491-4.

7.Gholizadeh, M., Tavassoli, M., Rezaei, F., Nikousefat, Z. (2015). Evaluation of histopathological features of Argas reflexus bite in pigeon. Iranian Journal of Veterinary Science and Technology, 6(2); 29-41.

8.Haag-Wackernagel, D., Bircher, A.J. (2010). Ectoparasites from feral pigeons affecting humans. Dermatology, 220(1); 82-92.

9.Hilger, C., Bessot, J.C., Hutt,N., Grigioni, F., de Blay, F., Pauli. G., Hentges. F. (2005). IgE-mediated anaphylaxis caused by bites of the pigeon tick Argas reflexus: cloning and expression of the major allergen Arg r 1. Journal of Allergy and Clinical Immunology, 115(3): 617-622.

10.Kleine-Tebbe, J., Heinatz, A., Gräser, I., Dautel, H., Hansen, G.N., Kespohl, S. (2006). Bites of the European pigeon tick (Argas reflexus): Risk of IgE-mediated sensitizations and anaphylactic reactions. Journal of Allergy and Clinical Immunology, 117(1); 190-195.

11.Klotz, J. H., Klotz, S. A., Pinnas, J.L. (2009). Animal bites and stings with anaphylactic potential. Journal of Emergency Medicine, 36; 148-156.

12.Latif, A. A., Maina, J. N., Dhadialla, T.S, Nook. S. (1990). Histological reactions to bites of Amblyomma variagatum and Rhipicephalus appendiculatus (Acari: Ixodidae) fed simultaneously on naive or sensitized rabbits. Journal of Medical Entomology, 27(3); 316-323.

13.Latif, A. A., Punyua, D. K., Capstick, P. B., Nokoe, S., Walker, A. R., Fletcher, J. D. (1991). Histopathology of attachment sites of Amblyomma variegatum and Rhipicephalus appendiculatus on zebu cattle of varying resistance to ticks. Veterinary Parasitology, 38(2-3); 205-213.

14.Mans, B. J., Andersen, J. F., Schwan, T. G, Ribeiro, J.M. (2008). Characterization of anti-hemostatic factors in the argasid, Argas monolakensis: implications for the evolution of blood-feeding in the soft tick family. Insect Biochemistry and Molecular Biology, 38(1); 22-41.

15.Masina,S., Broady, K.W. (1999). Tick paralysis: development of a vaccine. International Journal for Parasitology, 29(4); 535-41.

16.McGinley-Smith, D. E., Tsao, S. S. (2003). Dermatoses from ticks. Journal of the American Academy of Dermatology, 49(3); 363-392.

17.Mohi El-Din, M. M. (2010). Pathological studies on naturally Argas reflexus-infected squabs. Minufiya Vet, 7(1); 175-182.

18.Sirianni, M. C., Mattiacci, G., Barbone,B., Mari, A., Aiuti, F., Kleine-Tebbe, J. (2000). Anaphylaxis after Argas reflexus bite. Allergy (Copenhagen), 55(3); 303-307.

19.Soulsby, E. J. L. (2012). Helminths Arthropods and Protozoa of Domesticated Animals, 19Th ed. EWP. Pp; 321-368.

20.Tavssoli, E., Zare, S., Ghaderi, P. F., Tehrani, A. A., Tavassoli, M. (2007). Histopathological features of Ornithodoros lahorensis bite on rat. Iranian Journal of Parasittology, 2 (4); 17-24.

21.Venzal, J. M., Estrada-Peña, A., de Luco. D. F. (2007). Effects produced by the feeding of larvae of Ornithodoros aff. puertoricensis (Acari: Argasidae) on laboratory mice. Experimental and Applied Acarology, 42(3);217-23.

22.Vial, L. (2009). Biological and ecological characteristics of soft ticks (Ixodida: argasidae) and their impact for predicting tick and associated disease distribution. Parasite, 16(3); 191-202.

23.Wall, R., Shearer, D. (1997). Veterinary entomology, 1th Chapman and Hall International Thompson Publisher Co. London. Pp;96-149..