Extraction of drugs in water Samples by Carbon Nanotubes modified and Measurement with Ultraviolet-Visible Spectrometry
Subject Areas :ali moghimi 1 * , Shaghayegh Donyagard Vajed 2 , Fariborz Aziznejad 3
1 - Associated professor analytical chemistry Department of Chemistry, Varamin( Pishva )Branch Islamic Azad University, Varamin, Iran
2 - Department of Chemistry, Varamin( Pishva )Branch Islamic Azad University, Varamin, Iran
3 - Department of Chemistry, Varamin( Pishva )Branch Islamic Azad University, Varamin, Iran
Keywords: Ciprofloxacin, Solid phase extraction, carboxyl conjugated carbon nanotubes, Spectrophotometry,
Abstract :
In this method, the use of drugs continues to increase which leads to an increase in environmental pollution; as a result, drug control is a common practice in many laboratories. This method is dedicated to improving a method to determine small amounts of Ciprofloxacin in a water and biological sample. In this study, new techniques were applied for solid phase extraction of insignificant amounts of Ciprofloxacin in water samples by carbon nanotubes and its measurement with ultraviolet-visible spectroscopy in biological samples. These techniques are two-phase systems in which donor phases are Ciprofloxacin-containing aqueous samples and acceptor phases are amino-functionalized carbon nanotubes. The experiments were carried out in two stages of extraction from desolate water samples of Ciprofloxacin using methanol as solvent and the desolate samples were taken to UV-Vis spectrophotometer for further analysis. This method is inexpensive, simple and fast, and is consistent with many of the existing machine methods. Extraction parameters such as the effect of desolating organic solvents, pH of donor and acceptor phases, extraction time, desolation time, mixing speed, volume of donor phase and surfactant effect were optimized and quantitative investigations and measurements were done under optimum conditions. The techniques mentioned enjoy many advantages including short extraction time, low consumption of organic solvents, deleting the effect of previous experiments, low detection limit, and high concentration factor. Concentration factor and detection limit for Ciprofloxacin were 10 and 9.51 μg, respectively. the relative standard deviation was 1.12% for Ciprofloxacin and R2=0.9958.