The effect of taking some amino acids on liver damage indices in response to eccentric resistance exercise in non-athlete men.
Subject Areas : Physical Activity and Health
Adnan Fatahi
1
(
Academic staff
)
Keywords: Eccentric Contraction, Amino Acids, Exercise, Supplementation, Liver Injury,
Abstract :
The purpose of this research was to investigate the taking some amino acids on the muscle damage in response to eccentric contraction exercise. For this purpose, 24 inactive healthy young men volunteered were randomly divided into two supplement and placebo groups. The subjects performed a session of eccentric contraction of knee extension at intensity of 70 percent of one repetition maximum. The subjects in the supplement group consumed L-glutamine-L-arginine for three days (12 g/day). Before supplementation, before, 24 and 48 hours after the exercise, blood samples were collected and used for ALT, AST and ALP analysis. The results showed that eccentric contraction increased the serum levels of ALT, AST and ALP in 24 hours and 48 hours after the exercise (P<0.05). Also, the results showed that the consumption of L-glutamine-L-arginine supplement for three days has no effect on the resting concentration of liver enzymes (P>0.05). In addition, although serum levels of ALT, AST and ALP increased in 24 hours after exercise, but this increase was not statistically significant. Also, the results showed that, compared to the placebo group, the consumption of L-glutamine-L-arginine supplement prevented the increase in serum levels of ALT (P<0.001), AST (P=0.004), and ALP (P<0.001) at 24 and 48 hours after exercise. Overall, it can be concluded that L-glutamine-L-arginine supplementation prevents eccentric contraction-induced liver damage.