Survey of plasma alterations of hepcidine, cholinesterase, and total sialic acid in sheep with naturally infected Sarcocystosis
Subject Areas : Large Animal DiseasesAmin Amirzadeh 1 , Sohrab Rasouli 2 *
1 - Student of veterinary medicine, faculty of veterinary medicine, Islamic Azad university branch Urima-Iran
2 - Associate Professor of Pathobiology Department, Islamic Azad University, Urmia Branch, Urmia- Iran
Keywords: Sarcocystis, hepcidine, cholinesterase, total sialic acid, sheep,
Abstract :
Sarcocystis parasitic protozoa are one of the most common parasites of domestic animals and in some intermediate hosts such as cows and sheep it leads to severe infections due to the direct relationship of these animals with humans, infestation in human societies is also an important health problem. The present study was also conducted with the aim of studying the plasma changes of hepcidin, cholinesterase, and total sialic acid in sheep suffering from Sarcocystis. Considering that hepcidin generally plays an active role in the pathological process of many iron disorders in the body, it is expected that the measurement of its concentration in the biological fluids of the body will help in the diagnosis of diseases. Cholinesterase is one of the most important enzymes that is needed for the proper functioning of the nervous system. Sialic acids are present in many mammalian tissues so their concentration increases in inflammatory diseases and other diseases. In this study, blood samples were taken from 80 sheep affected with Sarcocystis and were analyzed in two groups, control, and patient. The statistical results show that the studied parameters in the sick sheep had a significant increase compared to the control group (P<0.05).