Evaluation of serumic Uric acid,Total Protein, Albumin, Calcium and Phosphorus levels in laying hens afflicted by the gout syndrome

Subject Areas : Veterinary Clinical Pathology

بهرام Amouoghli Tabrizi ¹ , حسین Nikpiran ² , SH Halabi ³

1 - Department of Clinical Sciences, Faculty of Veterinary Medicine, Tabriz Branch, Islamic Azad University, Tabriz, Iran
2 - Department of Clinical Sciences, Faculty of Veterinary Medicine, Tabriz Branch, Islamic Azad University, Tabriz, Iran
3 - Graduate of Veterinary Medicine, Tabriz Branch, Islamic Azad University, Tabriz, Iran

Received: 2010-09-27 Accepted : 2011-02-15 Published : 2011-02-20

Keywords: total protein, Calcium, Layer, phosphorus, albumin, Gout, Uric acid,

Abstract :

Gout syndrome is accounted for one of the prevalent causes of mortality in poultry farms. Gout is recognized by deposition of urates in kidneys, on serous surfaces of the heart, liver, mesenteries, air sacs and peritoneum. In some cases, these deposits may be observed on surfaces of muscles, synovial sheaths of tendons and joints, too. These deposits are like chalky coating and appear grossly. Gout could be seen in two forms, articular gout and visceral gout, and it is a disease with numerous causes.  The causing factors of the gout are classified in three groups which consist of nutrient and management factors, infectious factors, and toxic factors. For evaluation of biochemical parameters in gout disease, we surveyed and diagnosed in three farms of egg laying poultry breeding (HY-Line) affected to gout syndrome during spring and summer of 1386. In this study, from the above- mentioned poultry farms a number of 20 affected, and 20 healthy chickens (totally 120) were chosen and Blood samples of all animals were collected from wing veins and their sera were harvested by centrifuging and the levels of Uric acid, Total Protein, Albumin, Calcium and Phosphors parameters were measured by diagnostic laboratory kits. After taking blood, they were autopsied, and according to autopsy signs and syndromes, the diagnosis of gout was confirmed. Results of this study showed  significant increase on mean serumic Uric acid, Total Protein, Albumin, Calcium and Phosphorus in chickens affected by gout in comparison with the  healthy groups(p<0.05). In conclusion, with the measurement of these parameters in the laboratory, one could diagnose the gout syndrome even before the clinical signs become apparent. 

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