Review of Micro-Particles of Hydroxyapatite Nanoparticles by Ball Milling

Subject Areas : Journal of Simulation and Analysis of Novel Technologies in Mechanical Engineering

F. Fardi Pour ¹ , M. Najafi Anaraki ² , M. Karmian ³

1 - BSc Student, Department of Electrical Engineering, Khomeinishahr Branch, Islamic Azad University, Isfahan, Iran
2 - BSc Student, Department of Mechanical Engineering, Khomeinishahr Branch, Islamic Azad University, Isfahan, Iran
3 - Assistant Prof. , Department of Mechanical Engineering, Khomeinishahr Branch, Islamic Azad University, Isfahan, Iran.

Received: 2016-01-19 Accepted : 2016-01-19 Published : 2014-02-20

Keywords: XRD, Ball milling, Hydroxyapatite nanoparticles, Hardstvnayt graph,

Abstract :

Hydroxyapatite (HA) is the most important bioactive ceramics because of biocompatibility and structural similarity to the mineral part of bones and teeth of broad clinical application in the field of dentistry, orthopedic and coatings are Biomaterials. The aim of this study was to construct nano-hydroxyapatite micro particles using calcite, silica and zinc oxide using ball milling, powder, these three compounds, crushed and then molded into a cylindrical shape, pressed and put in oven a. The review ray diffraction X (XRD) suitable for milling, baking time and temperature samples obtained. The graph of the analysis of the samples was compared with HS. According to the results, the sample A with 10 hours of milling, temperature and heating time of 2 hours C˚ 1100, most of the other samples produced Hardstvnyt product

References:

[1] خواص و کاربرد پزشکی بیومواد فلزی، فتحی/ محمدحسین مرتضوی/ وجیهه‌السادات، انتشارات ارکان دانش،1382.

[2]دکتر محمد حسین فتحی، خواص و کاربرد پزشکی بیوسرامیک ها، انتشارات ارکان دانش،1388.

[3] Lao L., Wang Y., Zhu Y., Zhang Y., Gao C., Poly(lactide-co-glycolide)/hydroxyapatite nanofibrous scaffolds fabricated by electrospinning for bone tissue engineering, Journal of Materials Science: Materials in Medicine, vol. 22, No. 8, 2011, pp. 1873 – 1884.

[4] Hayati A.N., Hosseinalipour S.M., Rezaie H.R., Shokrgozar M.A., Characterization of poly (3-hydroxybutyrate) / nano-hydroxyapatite composite scaffolds fabricated without the use of organic solvents for bone tissue engineering applications, Materials Science and Engineering, vol. 32, No. 3, 2012, pp. 416–422.

[5] Zadegan S., Hosainalipour M., Rezaie H.R., Ghassai H., Shokrgozar M.A., Synthesis and biocompatibility evaluation of cellulose/hydroxyapatite nanocomposite scaffold in 1-n-allyl-3-methylimidazolium chloride, Materials Science and Engineering , vol. 31, No. 5, 2011, pp. 954–961.

[6] Beskardes I.G., Gumusderelioglu M., Bioact J., Biocompat, Biomimetic Apatite-coated PCL Scaffolds: Effect of Surface Nanotopography on Cellular Functions, Journal of Bioactive and Compatible Polymers, vol. 24, No. 6, 2009, pp. 507–524.

[7] Zreiqat H., Ramaswamy Y., Wu C., Paschalidis A., Lu Z., James B., The incorporation of strontium and zinc into a calcium–silicon ceramic for bone tissue engineering, Biomaterials, vol. 31 , No. 11 , 2010, pp. 3175 – 3184.

 [8] Woodruff M.A., Hutmacher D.W., The return of a forgotten polymer—polycaprolactone in the 21st century, Progress in Polymer Science, vol. 35 , No. 10, 2010, pp. 1217–1256.

[9] Jose M.V., Thomas V., Johnson K.T., Dean D.R., Nyairo E., Aligned PLGA/HA nanofibrous nanocomposite scaffolds for bone tissue engineering, Acta biomaterialia, vol. 5, No. 1,  2009, pp. 305–315.

[10] Prabhakaran M.P., Venugopal J., Ramakrishna S., Nanostructured biocomposite substrates by electrospinning and electrospraying for the mineralization of osteoblasts, Acta biomaterialia, vol. 5, No. 11, 2009, pp. 2884-2893.