Responses of proinflammatory cytokines (IL-6, IL-1ß) and insulin resistance to a long time aerobic activity in middle-aged smokers

Subject Areas : Effects of Movement and Exercise in Health

Saqqa Farajtabar Behrestaq ¹ ( Assistant Professor, Department of Physical Education and Sport Sciences, Qaemshahr Branch, Islamic Azad University, Qaemshahr, Iran. )

Received: 2022-12-25 Accepted : 2023-02-10 Published : 2022-12-22

Keywords: Aerobic exercise, Keywords: Insulin resistance, proinflammatory cytokines, middle-aged smokers,

Abstract :

Background and Purpose: Solutions such as exercise interventions will be able to reduce blood glucose levels and improve the inflammatory profile in the presence of continued smoking. The present study was conducted with the aim of the response of pro-inflammatory cytokines (IL-6, IL-1ß) and insulin resistance to a long-term aerobic activity in middle-aged smokers.Material and Methods: In this semi experimental study, the study sample consisted of 28 middle-aged men (30 to 45 years old) smokers who participated in the present study in an available manner.The experimental group then participated in an endurance training program three sessions per week for 8 weeks. 48 hours after the last training session, blood samples were taken again to measure the dependent variables as well as anthropometric indices (post-test) and were compared by independent and dependent t-tests.Results: 8 weeks of aerobic training with 3 sessions per week improved the determinants of type 2 diabetes and IL-1ß levels in middle-aged male smokers.Conclusion: 8 weeks of aerobic exercise 3 sessions per week is associated with improved determinants of type 2 diabetes and IL-1B levels in middle-aged male smokers. However, serum IL-6 levels did not change significantly in response to aerobic exercise.