Assessment of the biological performance of a Ti-6Al-4V/Ti double layer structure created through spark plasma sintering.

Subject Areas : journal of New Materials

Alireza Sharifi ¹ , Sahar Mollazadeh Beidokhti ² , Jalil Vahdati Khaki ^{3 *}

1 - MSc student of Materials Engineering, Department of Materials Engineering and Metallurgy, Ferdowsi University of Mashhad, Mashhad, Iran
2 - Assistant prof. of Materials Engineering, Department of Materials Engineering, Ferdowsi University of Mashhad, Mashhad, Iran
3 - Professor, Department of Materials Engineering and Metallurgy, Ferdowsi University of Mashhad, Mashhad, Iran

Received: 2024-11-25 Accepted : 2025-01-19 Published : 2024-08-05

Keywords: Assessment of the biological performance of a Ti-6Al-4V/Ti double layer structure created through spark plasma sintering,

Abstract :

Nowadays, the replacement of damaged  tissue with implants is inevitable. The most important materials for creating implants are metals with high deformability and exceptional mechanical properties. However, the high Young's modulus of metallic materials leads to a stress shield effect. It is necessary, therefore, to design the implant structure in a way that, in addition to maintaining other mechanical properties, it also features a modified Young's modulus. In this study, a two-layer structure (Ti-6Al-4V/Ti) was designed and manufactured so that the alloy core maintains mechanical properties, including compressive strength, while the shell reduces Young's modulus due to its porous structure. Irregularly shaped metal powder particles and the spark plasma sintering method were utilized to create porosity in the final sample at a working temperature of 900 °C and a baking time of 7 minutes. After the baking process, the results show a gradual change in the microstructure due to the allotropic transformation of titanium in areas near the interface. The core/shell interface was effectively filled by powder particles from both regions, resulting in a gradual change in composition. The residual porosity in the shell region was significantly higher than in the core . After the sample was stored for thirty days in a biomimetic solution, the concentration of ions in the medium decreased, leading to the formation of calcium-phosphate particles on the sample's surface. The pores in the structure were identified as suitable sites for the formation of calcium-phosphate particles.

References:

1. Bandyopadhyay, A., Mitra, I., Goodman, S. B., Kumar, M., & Bose, S. (2023). Improving biocompatibility for next generation of metallic implants. Progress in materials science, 133, 101053.‏
2. Verma, R. P. (2020). Titanium based biomaterial for bone implants: A mini review. Materials Today: Proceedings, 26, 3148-3151.‏
3. Tandon, B., Blaker, J. J., & Cartmell, S. H. (2018). Piezoelectric materials as stimulatory biomedical materials and scaffolds for bone repair. Acta biomaterialia, 73, 1-20.‏
4. Niinomi, M., & Nakai, M. (2011). Titanium‐based biomaterials for preventing stress shielding between implant devices and bone. International journal of biomaterials, 2011(1), 836587.‏
5. Shahzamanian, M. M., Banerjee, R., Dahotre, N. B., Srinivasa, A. R., & Reddy, J. N. (2023). Analysis of stress shielding reduction in bone fracture fixation implant using functionally graded materials. Composite Structures, 321, 117262.‏
6. Marin, E., Fedrizzi, L., & Zagra, L. (2010). Porous metallic structures for orthopaedic applications: a short review of materials and technologies. European Orthopaedics and Traumatology, 1, 103-109.‏
7. Bandyopadhyay, A., Espana, F., Balla, V. K., Bose, S., Ohgami, Y., & Davies, N. M. (2010). Influence of porosity on mechanical properties and in vivo response of Ti6Al4V implants. Acta biomaterialia, 6(4), 1640-1648.‏
8. Suárez, M., Fernández, A., Menéndez, J. L., Torrecillas, R., Kessel, H. U., Hennicke, J., ... & Kessel, T. (2013). Challenges and opportunities for spark plasma sintering: a key technology for a new generation of materials. Sintering applications, 13, 319-342.‏
9. Trevisan, F., Calignano, F., Aversa, A., Marchese, G., Lombardi, M., Biamino, S., ... & Manfredi, D. (2018). Additive manufacturing of titanium alloys in the biomedical field: processes, properties and applications. Journal of applied biomaterials & functional materials, 16(2), 57-67.‏
10. Lu, J. F., Zhang, Z. H., Liu, Z. F., & Wang, F. C. (2015). Sintering mechanism of Ti-6Al-4V prepared by SPS. Applied Mechanics and Materials, 782, 97-101.‏
11. Chaudhari, R., & Bauri, R. (2014). Microstructure and mechanical properties of titanium processed by spark plasma sintering (SPS). Metallography, Microstructure, and Analysis, 3, 30-35.‏
12. Osman, R. B., & Swain, M. V. (2015). A critical review of dental implant materials with an emphasis on titanium versus zirconia. Materials, 8(3), 932-958.‏
13. Kokubo, T., & Takadama, H. (2006). How useful is SBF in predicting in vivo bone bioactivity?. Biomaterials, 27(15), 2907-2915.‏
14. Kaschel, F. R., Vijayaraghavan, R. K., Shmeliov, A., McCarthy, E. K., Canavan, M., McNally, P. J., ... & Celikin, M. (2020). Mechanism of stress relaxation and phase transformation in additively manufactured Ti-6Al-4V via in situ high temperature XRD and TEM analyses. Acta Materialia, 188, 720-732.‏
15. Leyens, C., & Peters, M. (Eds.). (2006). Titanium and titanium alloys: fundamentals and applications. Wiley-vch.‏
16. Callister Jr, W. D., & Rethwisch, D. G. (2020). Materials science and engineering: an introduction. John wiley & sons.‏
17. Jackson, M. J., Kopac, J., Balazic, M., Bombac, D., Brojan, M., & Kosel, F. (2016). Titanium and titanium alloy applications in medicine. Surgical tools and medical devices, 475-517.‏
18. German, R. M. (1994). Powder metallurgy science. (No Title).‏
19. Ghosh, S. K., Saha, R., & Saha, B. (2015). Toxicity of inorganic vanadium compounds. Research on Chemical Intermediates, 41, 4873-4897.‏
20. Park, Y. J., Song, H. J., Kim, I., & Yang, H. S. (2007). Surface characteristics and bioactivity of oxide film on titanium metal formed by thermal oxidation. Journal of Materials Science: Materials in Medicine, 18, 565-575.‏
21. Chen, Y., Yang, W., Zhan, H., Zhang, F., Huo, Y., Zhao, Y., ... & Gu, Y. (2016). Tailorable burning behavior of Ti14 alloy by controlling semi-solid forging temperature. Materials, 9(8), 697.‏
22. Gaskell, D. R., & Laughlin, D. E. (2017). Introduction to the Thermodynamics of Materials. CRC press.‏
23. Rahaman, M. N., Day, D. E., Bal, B. S., Fu, Q., Jung, S. B., Bonewald, L. F., & Tomsia, A. P. (2011). Bioactive glass in tissue engineering. Acta biomaterialia, 7(6), 2355-2373.‏
24. Van Noort, R. (1987). Titanium: the implant material of today. Journal of Materials Science, 22, 3801-3811.‏