Hormone disrupting effects of nonylphenol ethoxylates on 17 ß – estradiol levels and ovary in Zebra cichlid ( Cichlasoma nigrofasciatum )

Subject Areas : Marine Biology

T. Maktabi ¹ , M. Roostaie ² , M. Mahdavi ³ , N. Nasiri ⁴ , H. Hosseinzadeh Sahhafi ⁵

1 - Dept. of Marine Biology, Faculty of Marine Science and Technology, Islamic Azad University Tehran North branch
2 - Dept. of Animal Science, Islamic Azad University Saveh branch
3 - Dept. of Marine Biology, Faculty of Marine Science and Technology, Islamic Azad University Sciences and Researches branch
4 - Islamic Azad University Varamin branch
5 - Islamic Azad University Varamin branch

Received: 2015-04-23 Accepted : 2014-09-01 Published : 2014-08-23

Keywords: oocytes, Cichlasoma nigrofasciatum, Nonylphenolethoxylate, hormone disruptor,

Abstract :

The present study investigatedsexually disrupting effects of a weak estrogen receptor agonist, nonylphenolethoxylale on 17 ß – estradiolproduction and ovary tissue in immatureZebra Cichlid (Cichlasoma nigrofasciatum). To determine the effects ofnonylphenol ethoxylale ( NPEO ) on female sex hormone of  Zebra cichlid, the fish were divided in 3weight groups ( < 4 g , 4 – 5 g and > 5 g ) and exposed to threeconcentrations ( 10 – 50 – 100 µg / L ) of NPEO in glass aquariums during 60days. At an estimated NPEO concentration of 50 and 100 µg / L, 17 ß – estradiolproduction significantly was increased (P < 0.01). Specialchanges were showed in 50 µg / L. Estadiol levels were 0.13 –0.70 ng /ml. Thisevidence of steroid hormone (17 ß – estradiol) levels showed that nonylphenolethoxylate (>10 µg / L ) could exert estrogenic effects through geneexpression and producting enzymes involving vitellogenesis and lead toproduction of grown oocytes in 50 µg / L of nonylphenol ethoxylale.