Preparation of 1,5-diaryl-3-(arylamino)-1H-pyrrol- 2(5H)-one derivatives using 1-methylpiperidinium hydrogen sulfate as an efficient catalyst

Subject Areas : Journal of the Iranian Chemical Research

Majid Ghashang ¹ , Mohammad Reza Mohammad Shafiee ² , Batool Hojati Najafabadi ³

1 - Department of Chemistry, Faculty of Sciences, Najafabad Branch, Islamic Azad University, Najafabad, Esfahan, Iran
2 - Department of Chemistry, Faculty of Sciences, Najafabad Branch, Islamic Azad University, Najafabad, Esfahan, Iran
3 - Department of Chemistry, Faculty of Sciences, Najafabad Branch, Islamic Azad University, Najafabad, Esfahan, Iran

Received: 2012-02-19 Accepted : 2012-06-20 Published : 2012-06-20

Keywords: Ionic liquid, 1, 5-diaryl-3-(arylamino)-1H-pyrrol-2(5H)-one, γ-lactam, 1-methylpiperidinium hydrogen sulfate,

Abstract :

A highly efficient and environmentally friendly synthesis of various 1,5-diaryl-3-(arylamino)-1H-pyrrol-2(5H)-ones catalyzed by 1-methylpiperidinium hydrogen sulfate via one-pot cyclo-condensation reaction ofaldehydes, amines and ethyl 2-oxopropanoate under ambient conditions has been explored. The presentmethodology offers several advantages such as good yields, simple procedure, shorter reaction times andmilder conditions and the products were purified without resorting to chromatography.

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