The Effect of hordeum vulgare L. on the development of lung tissues in the embryo of diabetic albino rats
Subject Areas : Journal of Comparative PathobiologyF. Arbabi, 1 , باقر Minae zangi, 2 , M. Sadooghi, 3
1 - ندارد
2 - ندارد
3 - ندارد
Keywords: Diabetic, Barely, development, Lung, Streptozotocin,
Abstract :
The goal of this research is to see how barley grains affect the development of lung tissues in theembryo of diabetic albino rats. An empirical study was done on 60 albino rats in four groups:1. Control, 2. Healthy + barely diet, 3. Diabetic + normal food, 4. Diabetic + barely diet. Aperitoneal injection of streptozotocin was used to develop diabetes in the rats. In the 21st day ofpregnancy the embryos were removed from the uterine horns, weighed and measured from headto tail. After tissue processing, H&E staining was done and the embryos’ lung tissues wereanalyzed using an optical microscope. The diabetic + normal food group showed lessdevelopment in bronchioles, alveoli and pneumocyte compared to the control group and hadhyperemic vessels and the most inflamed alveolar interstitial tissue. The diabetic + barely grouphad more developed bronchioles, alveoli and pneumocyte compared to the diabetic + normalfood group. This group has fewer hyperemic vessels and inflamed alveolar interstitial tissuecompared to the diabetic + normal food group. The embryos in the diabetic + normal foodincreased in weight while the diabetic + barely group had a slight decrease in weight. However,the decrease in weight was not significant. The head to tail length of the embryos in the diabetic+ normal food decreased compared to the control group and barely had no effect on the head totail length in the diabetic + barely group. It seems that barely is beneficial on the development oflung tissues in the embryo of diabetic albino rats. Barely can regulate the excess weight causedby diabetes to some extent; however, it has no effect on the reduction of head to tail lengthcaused by high glucose.