Green synthesis of naphthiridinone using multicomponent reaction of Melderumʼs acid and 4-aminoquinoline-2-one
Subject Areas : Iranian Journal of Organic ChemistrySeyyed Jalal Shams Najafi 1 , Maryam Ghazvini 2 , Atefeh Navabi 3
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Keywords: Solvent-free, Naphthiridinone, Acetophenone derivatives, Meldrum’s acid, 4-aminocoumarin, Dimethylcarbonate,
Abstract :
An efficient synthesis of naphthiridinone derivatives via reaction of 4-aminoquinoline-2-one, Melderum acid and ketones under solnent free conditions and room temperatureis described.