Green synthesis of naphthiridinone using multicomponent reaction of Melderumʼs acid and 4-aminoquinoline-2-one
Subject Areas : Iranian Journal of Organic Chemistry
Seyyed Jalal
Shams Najafi
1
()
Maryam
Ghazvini
2
()
Atefeh
Navabi
3
()
Keywords: Solvent-free, Naphthiridinone, Acetophenone derivatives, Meldrum’s acid, 4-aminocoumarin, Dimethylcarbonate,
Abstract :
An efficient synthesis of naphthiridinone derivatives via reaction of 4-aminoquinoline-2-one, Melderum acid and ketones under solnent free conditions and room temperatureis described.