Salicylic acid an efficient organocatalyst for synthesis of coumarins

Subject Areas :

1 - Post graduate center in Organic Chemistry and Department of Chemistry Hutatma Rajguru Mahavidyalaya, Rajgurunagar, Pune-410505 India
2 - Post graduate center in Organic Chemistry and Department of Chemistry Hutatma Rajguru Mahavidyalaya, Rajgurunagar, Pune-410505 India

Received: 2021-06-07 Accepted : 2021-06-07 Published : 2019-06-01

Keywords: phenol, Pechmann condensation, β-keto esters, Organocatalysis, Coumarins,

Abstract :

Various substituted coumarins were synthesized in high yield and purity by direct reaction of substituted phenol and β-keto esters in the presence of a catalytic amount of salicylic acid under solvent-free conditions. This method is simple, cost-effective, short reaction time, simple work-up procedure, and avoid the use of transition metals.

References:

Synthesis and spectroscopic study of a new diamidophosphoester, (4-CH3-C6H4O)((CH3)2CHNH)2P(O)
Print Date : 2023-09-18
One-pot synthesis of 1,2,4,5-tetrasubstituted Imidazoles using BiFeO3
Print Date : 2020-05-01
Tributyl hexadecyl phosphonium bromide as a new and efficient catalyst for the one-pot synthesis of 3,4-dihydropyrimidinones/thiones via a three component condensation reactions
Print Date : 2019-06-01
Theoretical study of HCX (NH2) (X= O, S, and Se) analogs in the gas phase: Electronic Structure, Natural Bond Orbital (NBO) & Natural Resonance Theory (NRT)
Print Date : 2022-03-01
Synthesis 3 and 4-Dihydropyrimidinone and Thiones using Multi-Walled Carboxylated Carbon Nanotube Catalysts
Print Date : 2019-08-01
Study of the effects of solvent and temperature on the Connections of the MTX and L-FMTX with single-walled carbon nanotubes using QM and MM
Print Date : 2022-09-01

Share To

Article Url

Salicylic acid an efficient organocatalyst for synthesis of coumarins