Effect of 6 Weeks of Aerobic Training and Cinnamon Supplementation on Resistin Gene Expression in Slow Twitch Muscle Tissue of Male Wistar Rats Fed with High Fat Diet
Subject Areas : Journal of Animal Biologynazanin abdollahzadeh 1 , yaser kazemzadeh 2 , saeid sedaghati 3 , Sanaz Mirzayan Shanjani 4 , zahra charbaghi 5
1 - Department of Physical Education and Sport Sciences, Islamshahr Branch, Islamic Azad University, Islamshahr, Iran
2 - Department of Physical Education and Sport Sciences, Islamshahr Branch, Islamic Azad University, Islamshahr, Iran
3 - Department of Physical Education and Sport Sciences, Islamshahr Branch, Islamic Azad University, Islamshahr, Iran
4 - Department of Physical Education and Sport Sciences, Islamshahr Branch, Islamic Azad University, Islamshahr, Iran
5 - Department of Physical Education and Sport Sciences, Islamshahr Branch, Islamic Azad University, Islamshahr, Iran
Keywords: Aerobic training, Resistin gene expression, Fast twitch muscle tissue, Slow twitch muscle tissue, High fat diet.,
Abstract :
The purpose of this research is to determine the effect of 6 weeks of aerobic training and cinnamon supplementation on the expression of the resistin gene in the slow twitch muscle tissue of male Wistar rats fed with a high-fat diet. The statistical sample of the research consists of 50 two-month-old male Wistar rats, which were randomly divided into five groups, and each group consisted of ten rats. The mice had daily access to 20 grams of pellets and 10-12 ml of water per 100 grams of body weight. The groups receiving high-fat food used high-fat food emulsion daily of 1.5 mg per kilogram of body weight. The aerobic exercise group participated in the aerobic exercise program on the electronic treadmill five days a week for six weeks. The cinnamon extract group received 200 mg per kilogram of body weight for 6 weeks. To analyze the data, dependent t-tests, one-way analysis of variance and, Tukey's follow-up were used. The results showed that the effects of a high-fat diet, combination of high-fat diet and aerobic exercise, the combination of high-fat diet and cinnamon, and a combination of high-fat diet, aerobic exercise and cinnamon on resistin gene variables in slow-twitch muscle tissue are significant (p ≥ 0.05). As a result, considering the optimal and favorable effects of taking cinnamon extract along with performing aerobic exercise on body weight and resistance gene expression and adjusting the adverse effects of consuming a high-fat diet, it is recommended to use cinnamon extract along with performing aerobic exercise.
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