Effect of Alcoholic Extract of Artichoke Leaves on Triglyceride and Blood Cholesterol Levels following Inhalation Toxicity in Male Rats
Subject Areas : Journal of Animal Biology
N. Khosravizad
1
(Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran)
Gh. Vaezi
2
(Department of Biology, Damghan Branch, Islamic Azad University, Damghan, Iran)
N. Hayati Roudbari
3
(Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran)
Keywords: artichoke, Lead toxicity, Blood triglyceride, Blood cholesterol,
Abstract :
Increased levels of blood cholesterol and triglyceride have many implications for humans and sufferers suffer from high costs annually. This research was conducted to investigate the effect of leaf extract of artichoke after lead inhalation in triglyceride and cholesterol levels in rats. In the first day, 5 groups of 6 male adult rats were contracted except for the control group under the lead inhalation. From the first day, 5 mg of extract gavage in the experimental groups at concentrations of 25, 50 and 100 mg/kg Mice weight was measured for 10 days. On the 10th day, the blood was collected from the heart and the remaining blood was separated and frozen with triglyceride and cholesterol kits for measurement. In this method (SPSS software, mean ± SD) method and Tukey test were used for data analysis.Blood cholesterol and triglyceride levels were determined by special kit after lead inhalation in the blood and after application of artichoke extract, p≤ 0.001 was statistically significant. The result was a decrease in the blood cholesterol and triglyceride levels in the artichoke leaf extract.due to its high antioxidant properties, leaf extract can reduce blood cholesterol and triglyceride levels. Therefore, Artichoke can be useful for reducing blood glucose in daily diet.
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