Anatomical and Intravenous Urography Investigation of the Kidneys, Ureters and Urinary Bladder in German Shepherd Dogs

Subject Areas : Journal of Animal Biology

Sana Loch Maleki ¹ (Department of Veterinary Medicine, Urmia Branch, Islamic Azad University, Urmia, Iran)
Mohammadreza Hosseinchi Gharehaghaji ² (Department of Veterinary Medicine, Urmia Branch, Islamic Azad University, Urmia, Iran)
Siamak Alizadeh ³ (Department of Veterinary Medicine, Urmia Branch, Islamic Azad University, Urmia, Iran)

Received: 2023-06-29 Accepted : 2023-08-23 Published : 2024-02-20

Keywords: Anatomy, urinary system, Intravenous Urography, German Shepherd Dog,

Abstract :

The aim of this study was to evaluate the anatomical structures of the urinary system in the nephrogram and pyelogram phases, and also to determine an accurate standard for the size of kidneys, ureters, and bladder in German shepherd dogs. This study was conducted on 14 German shepherd dogs with mean age of 2.7 years and an average weight of 35.12 kg. For urography studies, xylazine and diazepam were first administered to each animal to sedate, and then meglumine compound was slowly injected into the cephalic vein. Radiography was performed in the lateral and ventro-dorsal positions at 0, 1 and 5 minutes after injection, and then this procedure was continued every 5 minutes until the 60th minute to visualized the pyelogram phase completely. In the lateral radiographs of each dog, the length of the second lumbar vertebra body was measured to be used as an index in determining the standard size of the kidneys. Based on the results of this study, the mean ratio of the length, width and thickness of the left kidney and the ratio of the left ureter length to the length of the second lumbar vertebra body in German shepherd dogs were 2.69, 1.21, 1.24 and 6.47, respectively. The same ratios in the right kidney were 2.77, 1.30, 1.28 and 8.28, respectively. According to the radiological results, 15 minutes after the injection of the contrast media, the nephrogram and pyelogram phases are observed, which indicates the normal functioning of the kidneys. The exact standards obtained in this study can be used in the interpretation of results and clinical decisions to determine the normal and abnormal size of kidneys, ureters and bladder in German shepherd dogs.

References:

1. Ajadi R.A., Adetunji A., Omoerah V.O., Okoh J.U. 2006. Influence of dosage and chemical restraints on feline excretory urography. Journal of the South African Veterinary Association, 77(4):202-204.


2. Carlisle C.H., Brown A.S., Filippich L.J., Reynolds K., Reynolds W.T. 1989. Intravenous urography in the koala (Phascolarctos cinereus). Veterinary Radiology, 30(1):34-40.


3. Carneir R.K., Pereira T., Brun M.V., da Cruz I.C., Antunes B.N., Pozzobon R., Feliciano M.R. 2022. Excretory urographic, ultrasonographic, and cystoscopic characteristics of urinary bladder abscesses in a dog. Veterinary Radiology and Ultrasound, 63(4):7-10.


4. Chavez-Iniguez J.S., Cabrera-Aguilar S., Garcia-Garcia G., Armendariz-Borunda J. 2020. Acute kidney injury and acute liver failure in leptospira infection and Weil’s syndrome. Journal of Renal and Hepatic Disorders, 4(2):21-28.


5. Dimitrov R., Chaprazov T. 2012. An anatomic and contrast enhanced radiographic investigation of the rabbit kidneys, ureters and urinary bladder. Revue de Médecine Vétérinaire, 163(10):469-474.


6. Drost W.T., Henry G.A., Meinkoth J.H., Woods J.P., Lehenbauer T.W. 2000. Quantification of hepatic and renal cortical echogenicity in clinically normal cats. American Journal of Veterinary Research, 61(9):1016-1020.


7. Fielding C.L., Mayer J.R., Dechant J.E., Epstein K.L., Magdesian, K.G. 2021. Clinical and biochemical factors associated with survival in equids attacked by dogs: 28 cases (2008‐2016). Journal of veterinary internal medicine, 35(1):532-537.


8. Hardin R.A., Scott J.B., Haddy F. 1960. Relationship of pressure to blood flow in the dog kidney. American Journal of Physiology-Legacy Content, 199(6):1192-1194.


9. Hsieh E.S., Palm C., Segev G., Johnson EG., Leung K., Westropp J.L. 2022. Diagnostic yield of uroendoscopy compared to ultrasonography for evaluating lower urinary tract disorders in dogs. Journal of Veterinary Internal Medicine, 36(5):1700-1707.


10. Kealy J.K., McAllister H., Graham J.P. 2010. Diagnostic radiology and ultrasonography of the dog and cat - E-Book. 5th Edition, Elsevier Health Sciences, United States, America, pp: 297.


11. Kopp K.I., Schaub S., Peppler C., Acker A., von Pueckler K. 2020. Computed tomographic and sonographic findings in a dog with duplex kidney, ureter duplex and ectopic ureterocele. Tierärztliche Praxis Ausgabe K: Kleintiere/Heimtiere, 48(01): 44-48.


12. Lamb C.R., Dirrig H. and Cortellini S. 2018. Comparison of ultrasonographic findings in cats with and without azotaemia. Journal of Feline Medicine and Surgery, 20(10):948-954.


13. Lee S.K., Hyeong S., Kim S., Jeon C.Y., Lim K.S., Jin Y.B., Choi J. 2022. Comparison of static-fluid or excretory magnetic resonance urography with computed tomography urography for visualization of nondilated renal pelvises and ureters in healthy Beagles. American Journal of Veterinary Research, 83(3):229-238.


14. Lindquist E., Lobetti R., McFadden D., Ondreka‐Eley N., Roth A. 2021. Abdominal ultrasound image quality is comparable among veterinary sonographers with varying levels of expertise for healthy canine and feline patients. Veterinary Radiology and Ultrasound, 62(6): 705-710.


15. Lobacz M.A., Sullivan M., Mellor D., Hammond G., Labruyère J., Dennis R. 2012. Effect of breed, age, weight and gender on radiographic renal size in the dog. Veterinary Radiology and Ultrasound, 53(4):437-441.


16. Mahir K.A.Y.A., BUMİN A., ŞENEL O.O. 2010. Perirenal Pseudocyst in a Cat. Atatürk Üniversitesi Veteriner Bilimleri Dergisi, 5(3):147-153.


17. Maurya H., Kumar T., Kumar S. 2018. Anatomical and physiological similarities of kidney in different experimental animals used for basic studies. Journal of Clinical and Experimental Nephrology, 3(9):1-6.


18. Paul C.W., Didia B.C. 2012. The effect of methanolic extract of Moringa oleifera lam roots on the histology of kidney and liver of guinea pigs. Asian Journal of Medical Sciences, 4(1):55-60.


19. Piantedosi D., Di Loria A., Guccione J., De Rosa A., Fabbri S., Cortese L., Carta S., Ciaramella P. 2016. Serum biochemistry profile, inflammatory cytokines, adipokines and cardiovascular findings in obese dogs. The Veterinary Journal, 216:72-78.


20. Sohn J., Yun S., Lee J., Chang D., Choi M., Yoon J. 2016. Reestablishment of radiographic kidney size in Miniature Schnauzer dogs. Journal of Veterinary Medical Science, 78(12):1805-1810.


21. Veshkini A., Tavana M., Haghdost I.S., Masouleh M.N., Savojbolaghi S.H. 2011. Excretory Urography by Subcutaneous Injection of Iodixanol in Persian Squirrel (Sciurus Anomalous). Pakistan Veterinary Journal, 31(1):17-22.


22. Zachary J.F., McGavin M.D. 2012. Pathologic Basis of Veterinary Disease, 5th Edition, Elsevier Mosby, Missouri, pp: 1112-1115.


23. Zhou H., Li Y., Xu Y., Liu H., Lai Y., Tan K., Liu X., Ou Z., Chen W., Du H., Liu Z. 2021. Mapping renal innervations by renal nerve stimulation and characterizations of blood pressure response patterns. Journal of Cardiovascular Translational Research, 15(1):29-37.