Evaluation of the Effect of Satureja Edmondi on the Level of Pituitary-gonadal Hormones in Normal Rats and Those Induced by Chemical Kindling with Pentylenetetrazole

Subject Areas : Journal of Animal Biology

Somayeh Bohlouli ¹ , Gelavij Mahmoodi ²

1 - Department of Veterinary Medicine, Kermanshah Branch, Islamic Azad University, Kermanshah, Iran
2 - Department of Biology, Kermanshah Branch, Islamic Azad University, Kermanshah, Iran

Received: 2020-10-13 Accepted : 2021-01-13 Published : 2021-08-23

Keywords: Rat, Pentylenetetrazole, Satureja Edmondi, Pituitary-gonadal hormones,

Abstract :

Epilepsy is a neurological disorder that occurs in both men and women, but is more likely to occur in men than women. Epilepsy and many antiepileptic drugs cause reproductive disorders and reduce the quality of semen in men and increase the risk of infertility in men with epilepsy. some medicinal plants prevents the progression of the disease and the occurrence of epileptic seizures. The aim of this study was to evaluate the effect of Satureja edmondi on the level of pituitary-gonadal hormones in normal and epileptic rats with pentylenetetrazole. In this study, 48 Wistar rats were used. Rats were divided into two groups: normal and kindling with pentylenetetrazole, and each group was divided into three subgroups, control and treated with doses of 150 and 300 ppm Satureja edmondi essential oil. After 4 weeks, rats were examined for pituitary-gonadal hormone levels. Data analysis was performed by one-way ANOVA method and Tukey post hoc test and P

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