The Effect ofAqueous Extract of Borage (Anchusa italica) on Abortion in Syrian Mice FemaleWistar

Subject Areas : Journal of Animal Biology

آرزو زنگنه ¹ , شهلا روزبهانی ² , رامش منجمی ³

1 - گروه زیست شناسی، واحد همدان، دانشگاه آزاد اسلامی، همدان، ایران
2 - گروه زیست شناسی، واحد فلاورجان، دانشگاه آزاد اسلامی، اصفهان، ایران
3 - گروه زیست شناسی، واحد فلاورجان، دانشگاه آزاد اسلامی، اصفهان، ایران

Received: 2016-03-14 Accepted : 2017-05-21 Published : 2016-01-21

Keywords: Anchusa italic, absorbed embryos, formed embryos, healthyembryos,

Abstract :

Borage(Anchusa italica) belongs to the Boragynaceae Family. These plants contain fatty acids, seed oils, and chemical compounds.Any uterine bleeding associated with closed uterine cervix and bloody discharge in the first half of pregnancy is called a threatened to abortion, and in 50% of cases results in abortion.In this study, 30 female Wistar rats after mating and pregnancy that identified by vaginal plagues, were randomly divided into 5 groups:Acontrol group received normal saline intraperitoneally and 4 treatment groups receiving aqueous extract of borage with concentrations of 100, 200, 300 and 400 mg/kg.Injection for 5 days after day 7 of pregnancy was donedaily, and cesarean section was performed on day 16 of pregnancy.The number of absorbed embryos was considered as the abortionThe resultswere analyzedusingSPSS software.The resultsof the study showed that injections of extracts of borage effected on a number of absorbed embryos and the difference is statistically significant (p