The Effects of Hydroalcoholic Leaf Extract of Passiflora Caerulea on Activity of Liver Enzymes in Male Rats
Subject Areas : Journal of Animal Biology
طیبه Sadeghi
1
(گروه زیست شناسی، واحد کازرون، دانشگاه آزاد اسلامی، کازرون، ایران)
مهرداد Shariati
2
(گروه زیست شناسی، واحد کازرون، دانشگاه آزاد اسلامی، کازرون، ایران)
مختار Mokhtari
3
(گروه زیست شناسی، واحد کازرون، دانشگاه آزاد اسلامی، کازرون، ایران)
Keywords: liver enzymes, Rat, Hydroalcoholic leaf extract, Passiflora Caerulea,
Abstract :
Passiflora caerulea is one of medicinal plants and use in medicinal industry. Passiflora caerulea contain high anti oxidant combinations this combinations pain properties and are useful in curing have anti cancer and anti inflammatory and antiepilepsy, diarrhea, burn, hemorrhoid and in regulating liver enzymes. In this experiential study, 40 wistar male rats, use weighting about 195-200 g each were used in five groups eight including :control without received nothing, sham group received distilled water and 3 experimental groups receiving 150,300,600, mg/kg leaves of passiflora caerulea Hydro-alcohol extract respectively. According to obtained results, ALT, AST and Albumin in experimental group receiving the highest dose of the extract 600 mg/kg, pation in control group, meaningful in level. The Level of ALP, Total Protein, Creatinin and total body weight to comparison by control group not show significant changes and hydro alcoholic extract Passiflora cearulea Author decrease level BUN to experimental groups extraction of receiving. Hydro-alcohol extract of Passiflora caerulea leaves probably has a significant effect on hepatic activity. This effect by anti oxidant property active, mechanisms via like free radical control and peroxides neutralization and prevention of revive glutathione, evacuate and cell membrane stabilization and by stimulating DNA polymerase and increasing rRNA synthesis and finally relief liver cell.