The Effect of Camphor on Leydig Cells and Concentration of Testosterone and LH Hormones in Adult Male Mice, Balb/C Strain
Subject Areas : Journal of Animal Biologyمریم عابدینی 1 , وحید حمایت خواه جهرمی 2 , محسن فروزانفر 3 , حسین کارگر جهرمی 4
1 - دانشگاه آزاد اسلامی واحد جهرم، گروه زیست شناسی، جهرم، ایران
2 - دانشگاه آزاد اسلامی واحد جهرم، گروه زیست شناسی، جهرم، ایران
3 - استادیار دانشگاه آزاد اسلامی واحد مرودشت، گروه زیست شناسی، مرودشت، ایران
4 - عضو باشگاه پژوهشگران جوان دانشگاه آزاد اسلامی واحد جهرم، جهرم، ایران
Keywords: Testosterone, Mice, LH, camphor, Leydig cells,
Abstract :
Camphor is a plant from Lauraceae family. Investigations have shown that this plant has probably impression on controlling of sexual power. In this investigation, camphorandrsquo;s effect on spermatogenesis procedure has been worked out.Investigated parameters are the numbers of Leydig cells, sperm and testosterone concentration and LH. We use 36adult male mice with average weight of 34 andplusmn; 1 gr and age of 10 weeks.The animals divided to 9 groups with 4 animals in each group. The control group received no injection. The sham group received olive oil as camphorandrsquo;s dissolver. The treatment animals received camphor solution in concentration of 5,20 and 50 mg/kg(b.w) each amount 0/02 cc intraperitioneally for 2 weeks. Treatment group were sacrificed 1 day after the last injection and the posttreatment group 1 week after that. After injection, the animals were weighed.Then bloodsampling and sacrificed. The results show significant increase at P andlt; 0/05 in the number of Leydig cells and sperm and concentration of testosterone and LH in treatment animals than control animals. Thus due to increase of the mentioned hormones and the number of Leydig cells and sperm it is concluded that camphor may cause increasing of spermatogenesis.