Natural Catalyzed Synthesis, Characterization and Antibacterial Evaluation of Some Novel N-Benzylidene Aniline Derivatives Under Solvent Free Condition
Subject Areas : Chemistry and Chemical Engineering of all specializations
Keywords: lemon juice, benzaldehyde derivatives, Aniline derivatives, Antibacterial activity, green chemistry, N-benzylidene aniline,
Abstract :
In green chemistry we are always looking for materials that preparation or use of them does not pollute the environment. It is clear that lemon juice as a natural compound can be used as a green solvent-catalyst in a wide range of chemical reactions. In this study, lemon juice was used for condensation of aniline and benzaldehyde derivatives to prepare N-benzylidene aniline substituted. The synthesized compounds were characterized by FTIR, 1HNMR and 13CNMR spectroscopies. In the process of synthesis of these compounds no unnatural solvent were used, that emphasizes on the greenness of these reactions. Finally, antibacterial activities of synthesized compounds were studied against Gram-positive and Gram-negative bacteria strains. Results showed that the 3e compound has the highest antibacterial activity when compared to the other synthesized compounds.
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