Study of essential oil components of Zingiber officinale Essence and comparison of its anti-microbial property with Chlorhexidine Mouthwash on some Bacteria that cause Oral Infections

Subject Areas : The Application of Chemistry in Environment

Nima Mohammad Nejad Khiavi ¹ , Hojjat Eghbal ² , Neda Jahani ³ , Arezou Mohammadi ⁴ , Mehdi Ahmadi Sabegh ⁵ , zohreh Ghzi tabatabaei ⁶ , Amir Kishizadeh Mazraejahan ⁷

1 - Department of Food Science and Technology, Faculty of Agriculture, University of Tabriz, Tabriz, Iran.
2 - Department of Phytochemistry, Basic Sciences Research Center, Tabriz University, Iran.
3 - Doctor of Dentistry, Research & Development, Green Drug Reserchers, Meshkinshahr, Iran.
4 - Department of Oral and Maxillofacial Medicine, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.
5 - Department of Chemistry, Faculty of Basic Sciences, Islamic Azad University, Ahar Branch, Ahar, Iran.
6 - Department of Applied Chemistry, Ahar Branch , Islamic Azad University, Ahar, Iran
7 - Department of Biology, Faculty of Natural Sciences, University of Tabriz, Tabriz, Iran.

Received: 2021-02-21 Accepted : 2022-09-22 Published : 2021-03-21

Keywords: Ginger, Antibacterial agents, Essential oil, Chlorhexidine, Oral Infection,

Abstract :

Ginger (Zingiber officinale) is one of the indigenous medicinal plants of Iran and its antibacterial effects have been proven in some researches. In this research, the antibacterial effect of Ginger essence and comparison with chlorhexidine on some of common oral infection bacteria was studied. The essential oil of Ginger was extracted by Clevenger's apparatus, GC and GC/MS devices were used for analysis of essential oil compounds and accurate measurements of the compounds. The effect of the essential oil of the Ginger and control on the common bacteria of the oral infection were evaluated using two methods: Disc deffusion and minimum inhibitory concentration (MIC). The results of antimicrobial tests showed that ginger had a significant inhibitory effects on a variety of gram-negative and gram-positive bacteria. It was also found that the essential oil of this medicinal plant, in terms of antimicrobial properties, showed relatively similar results to chlorhexidine mouthwash. Ginger essential oil had been shown to have good antimicrobial effects against common bacteria in oral infections. As a result, the essential oil of this plant with different concentrations, after completing studies, can be an appropriate alternative for chemical drugs and chemical mouthwashes in the treatment of oral bacterial infections.