Post surgical adhesion prevention: Vitamin C or Satureja Khuzestanica

Subject Areas : Veterinary Clinical Pathology

ayda najafian ¹ , azin alavi ² , kambiz amjadigolpayegani ³ , sakineh dadipour ⁴ , ali safarimoradabadi ⁵ , soghra fallahi ⁶ , azita faramarzi ⁷

1 - متخصص زنان و زایمان، مرکز باروری و ناباروری خلیج فارس، استادیار دانشگاه علوم پزشکی هرمزگان، بندرعباس، ایران.
2 - استادیار دپارتمان بیولوژی دریایی، هیت علمی دانشگاه هرمزگان، بندرعباس، ایران.
3 - دامپزشک، اداره کل دامپزشکی هرمزگان، بندرعباس، ایران.
4 - دانشجوی کارشناسی ارشد، کمیته تحقیقات دانشجویی هرمزگان، بندرعباس، ایران.
5 - دانشجوی کارشناسی ارشد، کمیته تحقیقات دانشجویی هرمزگان، بندرعباس، ایران.
6 - دانشجوی دکترای تخصصی پژوهشی پزشکی مولکولی، مرکز تحقیقات پزشکی مولکولی، دانشگاه علوم پزشکی هرمزگان، بندرعباس، ایران.
7 - دانشجوی دکترای بیولوژی باروری، مرکز تحقیقات درمانی و پژوهشی ناباروری، دانشگاه علوم پزشکی یزد، یزد، ایران.

Received: 2013-06-17 Accepted : 2013-10-20 Published : 2013-05-22

Keywords: vitamin C, Satureja Khuzestanica, Abdominal Adhesions, Female Rat,

Abstract :

Abstract    Abdominal surgeries can result in intra abdominal adhesions. Since Satureja Khuzestanica is used for its anti oxidant, anti lipid, anti inflammatory and anti bacterial effects, it might also play a role in preventing intra abdominal adhesion. Therefore, this study was conducted in order to assess the effects of this plant compared with vitamin C in the prevention of post surgical intra abdominal adhesions.Forty rats were used for this experimental study and were randomly allocated into 4 groups of 10 rats. Ten ml of 0.9% normal saline, 250 mg/kg vitamin C, 250 mg/kg Satureja Khuzestanica, and both vitamin C plus Satureja Khuzestanica were used for the first, second, third and fourth group, respectively. Mazuji classification and pathology assessment were used to grade the amount of adhesion. According to our findings, vitamin C in addition to Satureja Khuzestanica is effective in preventing abdominal adhesions.

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