The effect of intramuscular injection of cyanocobalamin-iron dextran (Cyanoferrin) on primary parameters of haemogram and serum minerals in 20-day-old goat kids with Pica

Subject Areas : Veterinary Clinical Pathology

Samad Lotfollahzadeh ¹ , Mostafa Abdollahi ² , Parviz Noshirvani ³ , Hamidreza Mohammadi ⁴ , Morteza Abdollahi ⁵

1 - Associate Professor, Department of Internal Medicine, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
2 - Resident of Large Animal Internal Medicine, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
3 - Resident of Veterinary Clinical Pathology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
4 - Assistant Professor, Department of Clinical Science, Faculty of Veterinary Medicine, University of Semnan, Semnan, Iran.
5 - D.V.M Graduate, Faculty of Veterinary Medicine, Islamic Azad University, Garmsar Branch, Garmsar, Iran.

Received: 2020-05-19 Accepted : 2020-10-24 Published : 2021-07-23

Keywords: iron deficiency, goat kids, pica, Cyanoferrin, Haemogram,

Abstract :

Pica is one of the disorders with a high potential to induce numerous damages such as poisoning, impaction of gastrointestinal tract, botulism and weight loss in ruminant farms. The aim of this study was to determine the effect of intramuscular injection of cyanocobalamin-iron dextran (Cyanoferrin) on the initial parameters of haemogram and serum minerals in 20-day-old goat kids with Pica. The study was performed on 10 heads of 20-day-old mixed breed goat kids without Pica and 10 heads of 20-day-old mixed breed goat kids with Pica. The Pica unaffected group received isotonic saline treatment (one intramuscular injection, 3 ml) and the Pica affected group received Cyanoferrin treatment (one intramuscular injection, 3 ml). Before treatment and 10 days after treatment, blood samples were collected from all goat kids to determine CBC (complete blood cell count) and serum minerals. Data were analyzed using one-way repeated measures ANOVA and Post-hoc Tukey test at 95% confidence level. In goat kids with Pica, blood PCV, Hb and MCV and serum iron were significantly lower than goat kids without Pica (p<0.05). Treatment with Cyanoferrin significantly increased the blood PCV, Hb and MCV parameters and serum iron and Pica was treated in patients (p<0.05). The results of the present study indicated that Pica was associated with microcytic normochromic anemia in suckling goat kids, and the administration of a 3 ml cyanocobalamin-iron dextran compound during an intramuscular injection treated the patients.

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