Effect of subcutaneous injection of ceftiofur hydrochloride on postpartum uterine health in Holstein dairy cattle affected by dystocia and retained placenta

Subject Areas : Veterinary Clinical Pathology

Amir Ali Golzari fard ¹ , Roozali Batavani ² , Hamid Amanlou ³

1 - Veterinary Theriogenology student of Urmia faculty veterinary medicine
2 - Professor, Department of Theriogenology, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran.
3 - - Professor, Department of Animal Science and Nutrition, Faculty of Agriculture, Zanjan University, Zanjan, Iran.

Received: 2017-11-06 Accepted : 2019-02-26 Published : 2019-04-21

Keywords: Holstein dairy cow, Dystocia, Placenta retention, Uterine health, Ceftiofur hydrochloride,

Abstract :

Postpartum infection of the reproductive system is a major problem with financial costs in dairy cattle. Cefalosporins are among the most important and widely used antibiotics for treatment of postpartum uterine infections. This study examined the effect of postpartum ceftiofur hydrochloride injection on subsequent fertility rate of high risk (affected by dystocia, retained placenta and etc) dairy cattle.  A total of 300 dairy cows were divided equally into two groups of high risk cows (affected by dystocia, placental retention) designated as control and treatment groups. In the treatment group, ceftiofur hydrochloride was injected with the dose of 2.2 mg/kg SC for 5 days and in the control group, cows that had placental retention were treated with 3 intramuscular injections of oxytocin 50 IU every 8 hours after parturition and cows that had dystocia were left untreated.Ceftiofur hydrochloride injection significantly decreased the rate of uterine infections in the treatment group in comparison to the control group (p < /em><0.01). Also open days were significantly reduced in the treatment group (p < /em><0.05). First service rate was also improved significantly in the treatment group (p < /em><0.01). The results indicated that prevention of uterine infections is an essential part of postpartum fertility control in dairy cows. Ceftiofur hydrochloride injection at the rate of 2.2 mg/kg 24 hours after parturition can improve the subsequent fertility rate of high risk cows in dairy herds affected by peripartum and postpartum problems.

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