Preparation, Properties and Applications of Acrylic acid/ Acrylamide Based Hydrogels: A Review

Subject Areas : The Application of Chemistry in Environment

Mehrab Fallahi-Samberan ¹ ( Department Of Chemical Engineering )
Tannaz Soltanolzakerin- Sorkhabi ² ( Islamic Azad University- Ahar Branch )

Received: 2022-06-17 Accepted : 2022-09-14 Published : 2021-03-21

Keywords: Acrylamide, Acrylic Acid, Drug delivery system, Hydrogels, Polymers,

Abstract :

Hydrogels are among the well-liked biomaterials due to their biocompatibility, biodegradability and non-toxic properties which can be used in various applications in the field of engineering and medicine such as agriculture, pharmaceuticals, biomedical and cosmetic industry. Hydrogels are hydrophilic components that have the capability to absorb water or biological fluid. Hydrogels can be synthesized by polymer crosslinking. Applications, common synthesis and physical, chemical, mechanical and morphological properties of hydrogels are targeted to be understood through this review, focusing on acrylic acid and acrylamide based hydrogels and their application in medicine. Hydrogels have been used as a drug delivery system in varying medical areas from cardiology, oncology, immunology and wound healing to pain management. The main objective of this review is to gather information about the hydrogels such as acrylic acid, acrylamide, and preparation method of these hydrogels using N,N-methylenebisacrylamide (MBAA-crosslinker), ammonium persulfate (APS-initiator), tetramethylethylenediamine (TEMEDA-catalyst), and Fe+3 (ionic cross linker). future perspective of hydrogel materials is also considered in this review.