EFFECT OF THE ONE PERIOD OF BOLDENONE, RESISTANCE EXERCISE, AND JUJUBE EXTRACT ON STRUCTURAL DAMAGE OF PANCREATIC TISSUE IN MALE WISTAR RATS
Subject Areas : New studies in exercise metabolism and physical activitySayyed-Javad Ziaolhagh 1 , Ali-Reza Saadatifar 2 , Sayyed-Mostafa Tayyebi-Sani 3
1 - Department of Sport Physiology, Islamic Azad University, Shahrood Branch, Shahrood, Iran
2 - Department of Sport Physiology, Islamic Azad University, Shahrood Branch, Shahrood, Iran
3 - Department of Sport Physiology, Islamic Azad University, Shahrood Branch, Shahrood, Iran
Keywords: Resistance training, pancreas, Boldenone, Jujube extract,
Abstract :
Theme and Purpose: Today, the use of potent drugs is very common among athletes, and steroid hormones are being used to improve exercise performance. The aim of the present study was to investigate the side effects of anabolic Boldenone steroid on pancreatic tissue and the healing effect of jujube extract with resistance training on reducing these complications. Research method: 42 wistar male rats, aged 8-12 weeks, and weights 180-220 grams were studied. After two weeks of maintenance and getting used to the training protocols, the third week of exercise began. Subjects were randomly divided into 6 groups of 7 (Boldenone group and resistance training, Boldenone, Boldenone and Jujube extract, Boldenone without resistance training, Control and Sham) and were evaluated for desirable results.Results: The results showed that changes in weight gain in the hormone training group were significant (P=0), but in exercise groups alone (P=1.000) and hormone alone (P=0974) and jujube hormones (P> 0.05 - P =0989) has not been meaningful. High-dose steroids have been responsible for the destruction of pancreatic axins, islets of Langerhans and blood vessels.Conclusion: The results showed that the use of high-dose anabolic steroids results in the destruction of pancreatic tissue and exercise and jujube extracts can be effective in reducing the destructive effects of steroids.
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