Response of β-cell function and serum leptin to progressive aerobic exercise in obese males

Subject Areas : Physical Activity and Health

Davood Khorshidi ¹ (Faculty member/Islamic Azad University)

Received: 2021-10-07 Accepted : 2022-03-16 Published : 2022-03-21

Keywords:

Abstract :

Obesity is associated with metabolic disorders including type 2 diabetes. The objective of this study was to investigate the alternation of β-cell function and serum leptin following progressive aerobic exercise in obese males. Fifteen obese males adult (mean body mass index, 31.6 kg/m2) participated in this quasi -experimental study. Glucose, insulin, leptin, insulin resistance and β-cell function measured before and immediately after a single of aerobic exercise on a bicycle ergometer. Data were analyzed using paired t-test. A single session of progressive aerobic exercise resulted in a significant change in glucose and β-cell function; however, no significant changes were found in the insulin, leptin and insulin resistance. The results of this study showed that exercise may have a desirable effect on β-cell function independent of changes in insulin resistance and adipocytokines such as leptin.