Radiological and Histopathological Study of the Effects of Tragacanth Gum on Healing Femoral Defects in New Zealand Rabbits
Subject Areas :الهام مقتدایی 1 , davoud maleki 2
1 - هیات علمی گروه پاتوبیولوژی
2 - .........................
Keywords: Rabbit, Radius bone, Tragacanth gum, Radiology, Histopathology,
Abstract :
BInroduction & Objective: Skeletal injuries are common in animals and even humans today. Various methods have been used to treat and repair fractures. The prevalence of fractures and the and time-consuming methods used today have led us to sick a new way to treat bone defects. Material and Methods: Twelve new zealand rabbits weighing 1.5-2 kg were selected and kept for six weeks. Antiparasitic therapy and antibiotic therapy were performed. The rabbits' anterior limbs were shaved and entered the anesthesia phase. Then, in sterile conditions, the skin was exposed by cutting the skin and removing the radius muscles. The bone piece was removed with a mini-surgical mill and the sterilized tragacanth gum was placed in the bone cavity, the skin was sutured. After receiving antibiotics, rabbits were divided into control and sample groups and underwent radiology and histopathology during 2 and 6 weeks.Results: The results of the sixth week showed significant differences in bone tissue formation between the control and treatment groups (P <0.05). there was a statistically significant difference between the control and treatment groups in the fibroplasia variable in the sixth week (P <0.05). Comparative study of radiographic evaluation of the studied variables did not differ significantly between groups on different days. Conclusion: The results showed that tragacanth gum has a significant effect on bone repair and can be used in related disorders.
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