Alteration Viability of Breast Cancer Cell Lines in the Vicinity of an Inhibitor
Subject Areas :Mazdak Jamshidi 1 , fatemeh Keshavarzi 2 , Sabrieh Amini 3 , Ali Qeisarzadeh 4 , Kambiz Davari 5
1 - گروه زیستشناسی، واحد سنندج ، دانشگاه آزاد اسلامی،سنندج، ایران.
2 - Department of Biology, Sanandaj branch, Islamic Azad University, Sanandaj Branch, Sanandaj, Iran
3 - گروه زیست شناسی، واحد سنندج، دانشگاه آزاد اسلامی، سنندج، ایران.
4 - مرکز تحقیقات میکروبشناسی بالینی، دانشگاه علوم پزشکی ایلام، ایلام، ایران.
گروه زیست شناسی سه بعدی، دانشکده علوم، دانشگاه ایلام، ایلام، ایران.
5 - گروه زیست شناسی، واحد سنندج، دانشگاه آزاد اسلامی، سنندج ایران.
Keywords: inhibitors, Treatment, Highly Invasive Breast Tumors,
Abstract :
Inroduction & Objective: Breast carcinomas are very invasive tumors with poor prognosis that are more common in younger women (less than 50 years old). Although initially sensitive to chemotherapy, they are significantly more aggressive than other tumors of the molecular subgroup. The aim of this study was to find a new treatment for these cancers. Materials and Methods: The basis of the method was the construction of an inhibitor of cell surface receptors, in the first stage. Then, the effects of this inhibitor on breast cancer cell lines were examined by the routine tests. Results: The results showed that at appropriate concentrations of inhibitor, the life of the respective cell lines is significantly altered. Conclusion: The present study showed that the use of these methods can pave the way for future treatments.
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