Study of Anti - Antimutagen and Anti-Cancer Effect of Oxali Paldyvm and Nano Oxali Palladium by Ames Test (Ames) and the Metabolic System (Rat Liver Microsomes)
Subject Areas :Sedighe Mehrabian 1 , Mojtaba Vafajoo 2 , Adeleh Divsalar 3
1 - استاد دانشگاه آزاد اسلامی واحد تهران شمال و خوارزمی، تهران. ایران
2 - کارشناسی ارشد میکروبیولوژی واحد تهران شمال، تهران. ایران.
3 - استادیار گروه زیست شناسی و مولکولی دانشگاه خوارزمی، تهران. ایران.
Keywords: Microsomes, Palladium Nano Oxali, Oxali Palladium, cancer,
Abstract :
Inroduction & Objective: Deaths from cancer are rising in many countries. Oxali palladium and palladium nano oxali are anti-cancer drugs, the consumption of beneficial effects on the health of the consumer. The aim of this study was to evaluate the effects of anti-cancer, anti-mutation and oxali Paldyvm and palladium nano is oxali materials and waysMaterial and MethodIn this study, oxali palladium and palladium nanoparticles synthesized oxali anti-ejection and anti-cancer effects were used to. Anti-mutagenicity test was performed according to the Ames test. After comparing test results between samples tested positive control (sodium azide) and negative control (distilled water) was determined. Statistical analysis was performed using SPSS version 16.Results: Anti-mutation effect was observed in both the tested materials. Oxali contain mutations in 83% of palladium and palladium nano oxali was 77. The percentage of inhibition of mutant rat liver microsomes in between the tested materials in emergency situations to the absence of microsomes were not significantly different (P Conclusions:Both of oxali palladium and palladium nano oxali anti-ejection and anti-cancer effects were high.
