Synthesis of a new and recyclable Ce2Sn2O7 metal nanocatalyst for the three-component and efficient reaction (biginlli) of the 3,4-dihydropyrimidine (2H)one model

Subject Areas :

Fatemeh  Amarloo ¹ (Department of Chemistry, Basic Sciences, Islamic Azad University, Neyshabour, Iran.)
Rahelej  Zhiani ² (Azad University)
Alireza  Motavalizadehkakhky ³ (Department of Chemistry, Basic Sciences, Islamic Azad University, Neyshabour, Iran.)
Malihesadat  Hosseiny ⁴ (Department of Chemistry, Neyshabur Branch, Islamic Azad University, Neyshabur, Iran.)

Received: 2023-01-28 Accepted : 2023-05-15 Published : 2023-02-20

Keywords: nanoparticles, green chemistry, Green synthesis, catalyst, Recycling,

Abstract :

One of the important and useful reactions is dihydropyrimidinones, which are used in various fields, including pharmaceutical and biological activities. The aim of this study is to synthesize Ce2Sn2O7 NPs, to investigate their performance on the three-component and efficient reaction of 3,4-dihydropyrimidine (2H) of it. Analysis of the structure and morphology of nanoparticles was done by EDX, TEM, SEM, FT-IR analysis and the effect of various parameters such as solvent, temperature, time, amount of catalyst and substrate on the process of reactions was investigated. The results showed that the reaction of 3,4-dihydropyrimidine (2H) in the presence of 5 mg Ce2Sn2O7 catalyst at a temperature of 70 ℃ for half an hour had 92% efficiency in solvent-free conditions and the best efficiency in the presence of ethanol solvent. Ce2Sn2O7 nanocatalyst was separated by a magnet. After 10 uses, their performance decreased slightly. The nanoparticles used have outstanding properties such as thermal stability, high mechanical properties, good active sites, and a very large contact surface, allowing them to be used in several reactions.