An overview of the most important mechanisms and systems of targeted drug delivery

Subject Areas : biology

سید محمدجواد حسینی زاده ¹ (دانشجوی دکتری دانشگاه شهید بهشتی)

Received: 2016-04-19 Accepted : 2016-05-17 Published : 2016-05-21

Keywords: Drug targeting systems, Physical targeting, Drug targeting mechanisms, Passive targeting,

Abstract :

AbstractDrug delivery is one of the most important and most complex pharmaceutical branch that today due to use of other sciences is expanding dramatically. These improvements, especially in the field of drug delivery mechanisms and systems is very effective and useful. In this paper, drug targeting mechanisms such as Physical targeting, by progressing on the application of magnetic fields, ultrasound and electric fields is discussed. Passive targeting by its application on treatment of tumor tissue is explained. Active targeting with considering of the its Specificities is explained. Also delivery systems for drug targeting like Nanoscale Carriers including nano-liposomes, lipid nanoparticles, solid lipid nanoparticles and dendrimers is explained. At the end Targeted Prodrugs and Cellular Carriers and their progress as two other examples of drug delivery systems explained. Keywords: Drug delivery, Drug targeting, Drug targeting mechanisms, Drug targeting systems, Physical targeting, Passive targeting, Active targeting, Nanoscale Carriers, Targeted Prodrugs, Cellular Carriers