Effect of hydroalchoholic extract of Fraxinus extract in incisional wound healing in rats
Subject Areas : zoology
narges nazari
1
(
دانشجو
)
نسرین حیدریه
2
(
عضو هیئت علمی
)
Keywords: Wound healing, Rats, Incisional wound, Fraxinus extract extract,
Abstract :
Pato physiological process of wound healing involves the interaction of cellular and biochemical processes. According to Ash anti-inflammatory effect Fraxinus extract the aim of this study was to evaluate the effect of Fraxinus extract ointment incisional wound healing in rats can be. Method: Ash fruits and leafy branches after identification by the university herbarium, extract by Soxhlet extraction using rotary powder was prepared.Then ointment 70% and 35% as a percentage of the volume using eucerin (ointment base) and the dried extract was created.To induce colitis in male Wistar rats first (g200 ± 230) were anesthetized with ether and In the middle of incisional wound to the back of the animals during 2 (cm) and the thickness of the dermis was created. Rats in four groups (n = 8), no treatment (negative control), eucerin treatment (positive control), treated with ointment were 35% and 70% Fraxinus extract .Treatment every other day for . 14 days was done Before treatment, the wound was photographed by a digital camera and then with the help of AutoCAD software and the percentage of wound healing, wound surface area was determined.Data analyzed by SPSS software and ANOVA and Tukey test were analyzed.The results showed ointment 35% and 70% Ash significant increase in the percentage of wound healing compared to the control group were positive.Result :Fraxinus extract extract is accelerated wound healing in rats.
