The comparison of Cichorium intybusL. hydroalcoholic extract and Nystatin on the isolated Candida albicans from vaginal infection under in vitro conditions

Subject Areas : zoology

فاطمه ابراهیمی ¹ , kambiz Roshanaii ² , Fatemeh Jamallo ³

1 - دانشگاه آزاد اسلامی قم
2 - .استادیار گروه زیست شناسی ،دانشکده علوم پایه، دانشگاه آزاد اسلامی واحد قم، قم ، ایران
3 - .استادیار گروه زیست شناسی ،دانشکده علوم پایه، دانشگاه آزاد اسلامی واحد قم، قم ، ایران

Received: 2016-12-18 Accepted : 2017-01-27 Published : 2016-11-21

Keywords: Key word: Antifungal effect, Nystatin, hydroalcoholic extract Cichorium intybusL,

Abstract :

Background & Objective: With the increasing consumption of medical plants for medical treatment ,this topic of complementary medicine found a unique place. This study is the comparison of Cichorium intybusL. hydroalcoholic extract and Nystatin on the isolated Candida albicans from vaginal infection under in vitro conditions. Materials and Methods : C.Albicans was cultured on sabouraud dexterose agar containing chloramphenicol. Three series of 10 plant Cichorium intybusL. extract and a series of 10 of the disk impregnated with nystatin was prepared. On each plate, one plant extract disc, one nystatin disc (as positive control) and one blank disc (as negative controls) were placed. The mean diameter of non-growth halo around each plant extract was compared with the mean diameter of non-growth halo of positive control discs after 24 hours. Data was analysed by ANOVA statistical test (p<0.05). Results: The diameter of non-growth halo in nystation discs (28 mm) nystation were also more than Cichorium intybusL. discs(17 mm) (p<0.05). As well as the diameter of non-growth halo in Combination Cichorium intybusL and Nystatin discs(45 mm) was more than that for Cichorium intybusL discs(17 mm) and Nystatin discs(28 mm). Conclusion: Cichorium intybusL exhibited antifungal effects on C. Albincans But the effect of Nystatin on the lack of growth of Candida Albicans strains was greater than that in Cichorium intybusL. and combining the drug with extract on the lack of growth of Candida Albicans strains was greater than that in Nystatin. Key word: Antifungal effect, hydroalcoholic extract Cichorium intybusL. , Nystatin .