Evaluation of histopathological lesions leading to death in pink-collar parrots with neophobia

Subject Areas : Journal of Comparative Pathobiology

P. Mohamamdzadeh, ¹ (Department of Clinical Sciences, Faculty of Veterinary Medicine, Islamic Azad University, Sanandaj Branch, Sanandaj, Iran)
F. Najafi, ² (Gratuates student of Veterinary Medicine, Razi University of Kermanshah, Iran)

Received: 2022-08-26 Accepted : 2022-11-26 Published : 2022-11-26

Keywords: Neophobia, Histopathology, Pink Collar Parrot,

Abstract :

Many animals have a fear of novelty, which is known as neophobia. In the wild, avoiding new predators, meals, items, and places has an impact on life history and how animals adapt to new situations. However, because of the bird's anatomical structure, tolerance level, and physiology, this fear can occasionally cause irreparable harm and even death. The aim of this study was to evaluate the histopathological lesions leading to death in pink- collar parrots with neophobia. Necropsy was done and peripheral blood was obtained from the femoral vein and heart after a pink-collar parrot died suddenly. In addition, toxicological and biochemistry samples of bile, vitreous fluid, cerebral fluid, pericardial fluid, stomach contents, feathers, and samples of particular tissues (liver, kidney, and skeletal muscle) were taken. Pathological examinations of heart, lung, and brain tissues were also performed. It was clear that the right atrium had ruptured. The number of aortic cysts and the origin of the coronary artery had altered, indicating that cardiac arrest was more likely. Regurgitation, thickening or torsion of the cheeks' margins, rupture, perforation, calcification, fusion, or alterations in valve flushing were all visible problems in cardiac valves. The Papillary Muscles and the Corda Tendina had changed. Sudden death occurs at the end of a chain of events that leads to cardiac arrest; these events are commonly ventricular fibrillation (VF) or, less frequently, severe bradyarrhythmia.

References:

1. 
   
   
   
   1. 
      
      
      
      1. De Bruijn, R. and Romero L. M. Chronic stress reverses enhanced neophobia following an acute stressor in European starlings. Journal of experimental zoology. Part A, Ecological and integrative physiology. (2021); 335(2), 265–274.
      
      
      2. Lilly ML. Animal Behavior Case of the Month. J Am Vet Med Assoc. 2020; 257(5): 493-498.
      
      
      3. Suso-Ribera C, Fernández-Álvarez J, García-Palacios A, et al. Virtual Reality, Augmented Reality, and in Vivo Exposure Therapy: A Preliminary Comparison of Treatment Efficacy in Small Animal Phobia. Cyberpsychol Behav Soc Netw. 2019; 22(1): 31-38.
      
      
      4. Henderson LJ, Cockcroft RC, Kaiya H, Boswell T, Smulders TV. Peripherally injected ghrelin and leptin reduce food hoarding and mass gain in the coal tit (Periparus ater). Proc Biol Sci. 2018; 285(1879): 20180417.
      
      
      5. Miller R, Lambert ML, Frohnwieser A, Brecht KF, Bugnyar T, Crampton I, et al. Socio-ecological correlates of neophobia in corvids. Curr Biol. 2021; S0960-9822(21)01468-8.
      
      
      6. Clubb SL, et al. journal of Associationof Avian Veterinarians. 1990; 4(4): 222
      
      
      7. Ksepka, D. T. Balanoff, A. M., Smith, N. A., Bever, G. S., Bhullar, B. S., Bourdon, E., Braun, E. L et al. Tempo
      
      
      
      
      
      
      
      
      8. and Pattern of Avian Brain Size Evolution. Current biology.2020; 30(11): 2026–2036.
      
      
      9. Jiménez-Ortega, D. Kolm, N., Immler, S., Maklakov, A. A., and Gonzalez-Voyer, A. Long life evolves in large-brained bird lineages. Evolution; international journal of organic evolution. (2020);74(12): 2617–2628.
      
      
      10. Ebisawa K, Nakayama S, Pai C, Kinoshita R, Koie H. Prevalence and risk factors for feather-damaging behavior in psittacine birds: Analysis of a Japanese nationwide survey. PLoS One. 2021; 14: 16(7):
      
      
      11. Vera F, Zenuto R, Antenucci CD. Expanding the actions of cortisol and corticosterone in wild vertebrates: A necessary step to overcome the emerging challenges. Gen Comp Endocrinol. 2017; 246: 337-353.
      
      
      12. Frank A. Hartman. Heart Weight in Birds. The Condor, Volume 57, Issue 4, 1 July 1955, Pages 221–238, https://doi.org/10.2307/1365087.
      
      
      13. Basso C, Aguilera B, Banner J, Cohle S, d'Amati G, de Gouveia RH, di Gioia C, Fabre A, Gallagher PJ, Leone O, Lucena J, Mitrofanova L, Molina P, Parsons S, Rizzo S, Sheppard MN, Mier MPS, Kim Suvarna S, Thiene G, van der Wal A, Vink A, Michaud K; Association for European Cardiovascular Pathology. Guidelines for autopsy investigation of sudden cardiac death: 2017 update from the Association for European Cardiovascular Pathology. Virchows Arch. 2017 Dec;471(6):691-705. doi: 10.1007/s00428-017-2221-0. Epub 2017 Sep 9. PMID: 28889247; PMCID: PMC5711979.
      
      
      14. Virmani R., Chun P.K., Goldstein R.E., Robinowitz M., McAllister H.A. Acute takeoffs of the coronary arteries along the aortic wall and congenital coronary ostial valve-like ridges: association with sudden death. J Am Coll Cardiol. 1984;3:766–771.
      
      
      15. Neubauer S, Kolm P, Ho CY, Kwong RY, Desai MY, Dolman SF, Appelbaum E, Desvigne-Nickens P, DiMarco JP, Friedrich MG, Geller N, Harper AR, Jarolim P, Jerosch-Herold M, Kim DY, Maron MS, Schulz-Menger J, Piechnik SK, Thomson K, Zhang C, Watkins H, Weintraub WS, Kramer CM; HCMR Investigators. Distinct Subgroups in Hypertrophic Cardiomyopathy in the NHLBI HCM Registry. J Am Coll Cardiol. 2019 Nov 12;74(19):2333-2345. doi: 10.1016/j.jacc.2019.08.1057. PMID: 31699273; PMCID: PMC6905038.
      
      
      16. Drechsler C, Ritz E, Tomaschitz A, Pilz S, Schönfeld S, Blouin K, Bidlingmaier M, Hammer F, Krane V, März W, Allolio B, Fassnacht M, Wanner C. Aldosterone and cortisol affect the risk of sudden cardiac death in haemodialysis patients. Eur Heart J. 2013 Feb;34(8):578-87. doi: 10.1093/eurheartj/ehs361. Epub 2012 Dec 4. PMID: 23211232; PMCID: PMC3578266.
      
      
      17. Flannery, F. T. Oetgen, C. C., and Oetgen, W. J. Homicide by fright: the intersection of cardiology and criminal law. The American journal of cardiology. (2010); 105(1): 136–138.
      
      
      18. Terranova, C. Snenghi, R., Thiene, G., and Ferrara, S. D. Psychic trauma as cause of death. Medicine, science, and the law. (2011); 11–15.
      
      
      19. Hughes RK, Knott KD, Malcolmson J, et al. Apical Hypertrophic Cardiomyopathy: The Variant Less Known. J Am Heart Assoc. 2020; 9(5): e015294.
      
      
      20. Amin H. Z. Amin L. Z., and Pradipta, A. Takotsubo Cardiomyopathy: A Brief Review. Journal of medicine and life. (2020); 13(1): 3–7.
      
      
      21. Meo M, Bonizzi P, Bear LR, et al. Body Surface Mapping of Ventricular Repolarization Heterogeneity: An Ex-vivo Multi parameter Study. Front Physiol. 2020; 11: 933.
      
      
      
      
      
      
      
      
      22. Black N, D'Souza A, Wang Y, Piggins H, Dobrzynski H, Morris G, and Boyett, M R. Circadian rhythm of cardiac electrophysiology, arrhythmogenesis, and the underlying mechanisms. Heart rhythm. (2019); 16(2): 298–307.
      
      
      23. Berthelsen LF, van Diepen S, Steele AR, et al. Duration at high altitude influences the onset of arrhythmogenesis during apnea. European Journal of Applied Physiology. 2022; 122(2): 475-487.