Study of effect of Ginseng on testicular tissue after Orchidopexy operation in immature rat

Subject Areas : Journal of Comparative Pathobiology

Safavi, E., Mousavi, G. . ¹ ( . )

Received: 2017-02-12 Accepted : 2017-02-12 Published : 2017-06-22

Keywords: Ginseng, Testis, Cryptorchidism, Orchidopexy, Rat,

Abstract :

Perturbation of testicular descension into the scrotum result in cryptorchidism. After surgical correction of cryptorchidism (Orchidopexy), recovery of damaged testicular tissue, were observed gradually. The aim of present study, was to histological evaluation on the effect of Ginseng against testis after Orchidopexy in rat. In this study, 40 male Wistar rats (90-120 gr and 28 days old) randomly were divided in to 4 groups of 10 animals each. In first groups, after Orchidopexy, saline normal used orally for 30 days. In second groups, after Orchidopexy, Ginseng (500mg/kg/day) used orally for 30 days. In third groups, as a sham, after incision, testes were replaced from scrotum to abdominal cavity then returned to scrotum and used saline normal orally for 30 days. In fourth groups, as a healthy control, no operated. At the end of the experimental periods, testicular tissue samples were obtained for morphologic and histomorphometerical studies. The results were analyzed with one-way ANOVA and Tukey test and P 

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