Pathological and clinical study of feline lower urinary tract disease (FLUTD) with emphasis on the pathogenesis of uroliths
Subject Areas :Reza Yousefpour 1 , Amir Amniattalab 2 , kambiz Valiei 3
1 - FFaculty of Veterinary Medicine, Urmia Branch, Islamic Azad University, Urmia, Iran
2 - Department of Pathobiology, Faculty of Veterinary Medicine, Islamic Azad University, Urmia, Iran
3 - تبریز- خیابان 17 شهریور جدید- کوی شهید نعلبندی پور- بن بست نیلوفر- پلاک 247
Keywords: Cat, FLUTD, Uroliths, Bladder, Pathology,
Abstract :
This investigation was executed over a biennial period in the city of Tabriz, involving 348 felines across three veterinary medical facilities. Among the 348 felines assessed, 112 felines (31.18%) presented with bladder or urinary tract calculi. Furthermore, the prevalence of urinary calculi in male felines was markedly higher than in female felines (P=0.001). However, there was no substantial correlation between breed, age, and the incidence of urinary calculi in the examined felines (P<0.05). The examined felines were categorized into a cohort with calculi and concomitant pathology and a cohort with calculi alone. In hematological evaluations, there was significant anemia and neutrophilia in the cohort with calculi and concomitant pathology in comparison to the felines with calculi (P<0.05). Nevertheless, the hematological and biochemical parameters in the felines with calculi remained within standard ranges. Anemia was noted in animals with bartonellosis and hypoproteinemia, although not statistically significant in the juxtaposition of the two cohorts, was recorded in the calculi and concomitant pathology cohort (CKD patients). The type of calculi was documented in 90% of instances as struvite and 10% as calcium oxalate. In pathological examinations, hemorrhagic and chronic cystitis was observed in affected felines. The findings of this investigation indicated that in the majority of instances, the consumption of substandard dry nourishment, insufficient access to adequate hydration, and sedentary lifestyles combined with obesity represent the most critical determinants in the development of calculi and, consequently, feline lower urinary tract disease (FLUTD).
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