Detection of Nitrofurantoin using a Modified Glassy Carbon Electrode with Woolen Ball-shaped La3+/TiO2 Nanostructure as a Sensitive Electrochemical Sensor

Subject Areas : Nano

Mohammad Mehdi Foroughi ¹ , Shohreh Jahani ² , Soroush Rashidi ³ , Mehran Moradalizadeh ⁴

1 - Islamic Azad University, Kerman, Iran
2 - Bam University of Medical Sciences, Bam, Iran
3 - Department of Civil Engineering, Islamic Azad University, Kerman, Iran
4 - Department of Chemistry, Kerman Branch, Islamic Azad University, Kerman, Iran

Received: 2024-02-19 Accepted : 2024-05-12 Published : 2024-12-28

Keywords: Nitrofurantoin, Voltammetry, Lanthanum, Nanostructure, Titanium dioxide,

Abstract :

Specialists in disease diagnosis and biomedical chemistry have always sought to detect a variety of antibiotics, such as nitrofurantoin (NFT) in various matrices. The current attempt was also made to detect NFT in phosphate buffer solution using a glassy carbon electrode modified with as-fabricated woolen ball-shaped La3+/TiO2 nanostructure (WB-S La3+/TiO2-NS/GCE) according to techniques of cyclic voltammetry, chronoamperometry and differential pulse voltammetry. The effects of WB-S La3+/TiO2-NS result in an electrocatalytic-type response providing a significantly improved electroanalytical response compared to a bare unmodified GCE. The produced sensor was also strong in studying the concentration changes of NFT, with the limit of detection of 0.57 nM. Moreover, the proposed sensor was successful in sensing the NFT in real specimens, and exhibited appreciable stability and repeatability.