Water as a green solvent for fast and efficient synthesis of 1,5-benzodiazepines at room temperature by using Water-Tolerant Sulfonic Acid Nanoreactor Based on Tunable Ordered Porous Silica

Subject Areas : Journal of Nano Chemistry and Electrochemistry

GHolam Hossein Mahdavinia ¹ , Soheila Ghassamipour ²

1 - Department of Chemistry, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran
2 - Department of Chemistry, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran

Received: 2023-02-07 Accepted : 2023-06-18 Published : 2025-09-28

Keywords: ZrOCl2.8H2O on Montmorillonite K10, MCM-41-SO3H , Heterogeneous catalyst, 1, 5-benzodiazepines,

Abstract :

A rapid and new green synthesis of 1,5-Benzodiazepines is reported. The title compounds were prepared by the reaction of different 1,2-phenylenediamines and ketones in the presence of ZrOCl2.8H2O on montmorillonite K10 and MCM-41-SO3H as a nanocatalyst in water. These methods are simple, effective, better yield and environmentally friendly. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .