Identification of bacteria causing urinary tract infections in diabetic patients in Shahrekord city

Subject Areas : microbiology

Mohammad Rajabi ¹ (1. Department of Microbiology, Faculty of Basic Siences, Shahrekord Branch, Islamic Azad University, Shahrekord, Iran)
payam razeghi tehrani ² (عضوهیات علمی دانشگاه)
Hossein Khodabandeh shahraki ³ ()

Received: 2024-08-16 Accepted : 2024-08-16 Published : 2024-08-16

Keywords: assessment, bacteria, infections, diabetes, blood sugar,

Abstract :

Diabetic patients are extremely sensitive to infection and the infection is very risky. In this study, urine samples from 300 patients with type 2 diabetes mellitus in Shahrekord in 1394, instances of infection and infection-causing micro-organisms were isolated by culture and biochemical tests and molecular detection by PCR test for prove the existence of bacteria was carried out. E. coli was common organisms in these patients. Therefore, periodic exams and urine of diabetic patients for periodic testing and recommended strongly felt that based on the result Antibiogram, effective drug for treatment of urinary tract infection is selected. Results of this study show that the most common pathogen E. coli by 51% is administrative. In studies conducted in other parts of the world, these micro-organisms is known as the most common cause of UTI.

References:

1. Shaw JE, Sicree RA,, Zimmet PZ. 2010. Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Research Clinical Practice; 87(1): 4-14.
2. Greelings SE., Meiland R., and Hoepelmn A. 2002. Pathogenesis of bacteriuria in women with diabetes mellitus. Journal of Antimicrobial Agents.19: 539-545.
3. Balasoiu D., van Kessel KC., Van kats., Renaud HJ., Collet J., and Hoepolman AI. 1997. Granulocyte functions in women with diabetes and asymptomatic bacteriuria. Diabetes Care. 20:393–395.
4. Bertoni AG., Saydah S., and Brancati FL. 2001. Diabetes and the risk of infection related mortality in the US. Diabetes Care. 24 (3): 1004-10049.
5. Pozzilli P., and Lesli RDG. 1994. Infections and diabetes: Mechanisms and prospects for prevention. Diabetic Medicine. 11 (5): 935-941.
6. Carton JA., Maradona JA., Nuno FJ., Fernandez-Alvarez R., Perez-Gonzalez F., and Asensi V. 1992. Diabetes mellitus and bacteremia: A comparative study between diabetic and non diabetic patients. European Journal of Medicinal Chemistry.1 (4): 281-287.
7. Boyko EJ., Fihn SD., Scholes D., Abraham L., and Monsey B. 2005. Risk of Urinary Tract Infection and Asymptomatic Bacteruria among Diabetes and Non diabetic Postmenopausal Women. American Journal of Epidemioliology. 161 (7): 557-564.
8. Bonadio M., Boldirini E., Forrotti G., Matteucci E., Vigna A., Mori S., and Giampietro O. 2004. Asymptomatic bacteriuria in women with diabetes: in Xuence of metabolic control. Clinical Infection Disease. 38 (4): 41–45.
9. Mac Farlane IA., Brown RM, Smyth RW, Burdon DW, FitzGerald MG. Bactereamia in diabetics. J Infect 1986; 12: 213-219.
10. Wheat LJ.1980. Infection and diabetes mellitus. Diabets care. 3: 187-197.
11. نوروزی ج، کارگر م. (1380). مکانیسم مولکولی بیماری زایی باکتری¬ها. انتشارات جعفری. 450-440
12. ادیب فر، پ. (1375) میکروب شناسی پزشکی. انتشارات دانشگاه تهران، 504 -431.
13. Tajbakhsh E., Tajbakhsh S, Khamesipour F. (2015). Isolation and Molecular Detection of Gram Negative Bacteria Causing Urinary Tract Infection in Patients Referred to Shahrekord Hospitals, Iran. Iran Red Crescent Med J. 17(5): e24779.
14. Tajbakhsh E., Tajbakhsh S., and Khamesipour F. 2015. Isolation and Molecular Detection of Gram Negative Bacteria Causing Urinary Tract Infection in Patients Referred to Shahrekord Hospitals, Iran. Iran Red Crescent Medical Journal. 17(5): e24779.
15. Makuyana D., Mhlabi D., Chipfupa M., Muny T., and Gwan L 2002. Asymptomatic bacteriyria among outpatients with diabetes mellitus in an urban black population. Central African J Medical. 48(7.8):78-82.
16. Mendoza T., García de los Ríos M., Lafourcade M., Soto C., Durruty P., and Alvo M. 2002. Asymptornatic bacteriuria in type 2 diabetic women. Revista Medical the Chil. 130(9):1001-1007.
17. Sewify M., Nair Sh., Warsame S., Murad M., Alhubail A., Behbehani K., Al-Refaei F., and Tiss A. 2016. Prevalence of urinary tract infection and antimicrobial susceptibility among diabetic patients with controlled and uncontrolled glycemia in Kuwait. Journal of Diabetes Research. 3 (5): 1-7.
18. مهدی پور ع. علیزاده م. صابری س. بررسی شیوع UTI در افراد دیابتیک در بیمارستان سهند، مجله علوم پزشکی سنندج، شماره سوم، سال چهارم، 1382: 65-61.
19. علی زاده ب. (1383). شیوع UTI در افراد دیابتیک مراجعه کننده به کلینیک 17 شهریور یزد. مجله علمی پژوهشی دانشگاه علوم پژشکی یزد. شماره دوم، سال یازدهم، 59-54.
20. Geerlings SE., Stolk RP., Camps MJ, Netten PM., Hoekstra JB., and Bouter KP. 2000. Asymptomatic bacteriuria may be considered a complication in women with diabetes.diabetes mellitus women asymptomatic bacteriuria utrecht study group. Diabetes Care. 23 (6): 744-749.
21. Nitzan O., Elias M., Chazan B., and Saliba W. 2015. Urinary tract infections in patients with type 2 diabetes mellitus: review of prevalence, diagnosis, and management. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy. 8 (2):129–136
22. Zhanel GG., Nicolle LE., and Harding GK. 1995. Prevalence of asymptomatic bacteriuria and associated host factors in women with diabetes mellitus. Clinical Infectious Disease. 21 (3): 316-325.
23. Jarsiah P., Alizadeh A, Mehdizadeh E, Ataee R, Khanalipour N. 2014. Evaluation of antibiotic resistance model of Escherichia coli in urine culture samples at Kian hospital lab in Tehran, 2011-2012. Journal of Mazandaran University Medical Scienses. 24:78-83.
24. Chaurasia D., Shrivastava RK., Shrivastava S., Dubey D., and Songra M. 2015. Bacterial pathogens and their antimicrobial susceptibility pattern isolated from urinary tract infection in a tertiary care centre. International Journal of Pharmacy & Bio-Sciences. 1 (3): 20-24.
25. Molaabaszadeh H., Hajisheikhzadeh B., Mollazadeh M., Eslami K., and Mohammadzadeh Gheshlaghi N. 2013. Study of sensibility and antimicrobial resistance in Escherichia coli isolated from urinary tract infection in Tabriz city. Journal of Fasa Univesity Medical Science. 3 (2):3:149-154.