Biosynthesis, optimization and characterization of gold nanoparticles by lavender seed extract

Subject Areas : Developmental biology of plants and animals , development and differentiation in microorganisms

amin baghizadeh ¹ , sedigheh Zareie Dehseraji ² , hassan karimi-maleh ³ , Mohammad Ebrahimi ⁴

1 - Department of Biotechnology, Institute of Science and High Technology and Environmental Sciences, Graduate University of Advanced Technology, Kerman-Iran
2 - Payame Noor University
3 - Department school of Resources and Environment, University of Electronic science and Technology
4 - Payame Noor University Tehran Iran

Received: 2024-06-02 Accepted : 2024-12-20 Published : 2024-12-30

Keywords: Biosynthesis, Nanobiotechnology, Lavandula angustifolia, Seed extract, Gold nanoparticles ,

Abstract :

The tendency to produce and use nanoparticles is increasing due to their characteristics in medicine and industry. Today, metal nanoparticles, especially gold nanoparticles, are widely used in the fields of cancer treatment, pharmaceuticals, targeted transfer of biological compounds, production of cosmetics and many other industries. Among the methods of producing nanoparticles in the right size and amount, the cost-effective and biocompatible method of using plant tissues has attracted the attention of scientists. In this research, lavender seed extract was prepared by soaking in heat, and then by combining the extract with gold nitrate and diluting with deionized water, gold nanoparticles were produced. The factors affecting the production process of nanoparticles, including time, temperature and pH, were also determined by visible-ultraviolet absorption spectroscopic analysis, checking and optimal synthesis conditions, pH = 9.5, temperature 35 degrees Celsius and time 30 minutes. The results showed that with increasing temperature and time, the size and synthesis rate of nanoparticles increases and no nanoparticles were synthesized at acidic pH. Then, using XRD and transmission electron microscopy techniques, the size and structure of the produced nanoparticles were investigated. The results showed that the produced gold nanoparticles have a crystalline structure and are spherical and homogeneous with an average diameter of 5-30 nm. The Nyquist curve of simple carbon paste electrode and carbon paste modified with gold nanoparticles confirmed the electrical conductivity of gold nanoparticles and their presence in lavender seed extract.

References:

1. Ahmad N, Bhatnagar S, Saxena R, Iqbal D, Ghosh AK, Dutta R. Biosynthesis and Characterization of Gold Nanoparticles: Kinetics, in vitro and in vivo Study. Mater. sci. eng, 2017; 78(1):553-564.

2. Ankamwar B, Damle C, Ahmad A, Sastry M. Biosynthesis of Gold and Silver Nanoparticles using Emblica officinalis Fruit Extract, Their Phase Transfer and Transmetallation in an Organic Solution. J. Nanosci. Nanotechnol, 2005; 5(10):1665-1671.


3. Aromal SA, Vidhu VK, Philip D. Green Synthesis of Well-dispersed Gold Nanoparticles using Macrotyloma uniflorum. Spectrochim Acta A Mol Biomol Spectrosc, 2012; 85(1):99-104.

4. Asadi M, Baghizadeh A. Biosynthesis, Optimization and Characterization of Gold Nanoparticles by Hyoscyamus niger Seed Extract using Taguchi Method. Cellular. Molecular. Res 2024; doi: 10.22034/cmr.2024.7535.2553

5. Asadi M, Baghizadeh A. Optimization and Characterization of Biosynthesized Gold Nanoparticles by Oenothera biennis Seed Extract using Taguchi Method. J. Med. Plants, 2020; 19 (75) :102-117.


6. Das RK, Borthakur BB, Bora U. Green Synthesis of Gold Nanoparticles using Ethanolic Leaf Extract of Centella asiatica. Mater. Lett, 2010; 64(13):1445-1447.

7. Das RK, Gogoi N, Babu PJ, Sharma P, Mahanta C, Bora U. The Synthesis of Gold Nanoparticles using Amaranthus spinosus Leaf Extract and Study of Their Optical Properties. Adv. Mater. Phys. Chem, 2012; 2(4):275-276

8. Dinesh S, Karthikeyan S, Arumugam P. Biosynthesis of Silver Nanoparticles from Glycyrrhiza glabra Root Extract. Arch Appl Sci Res, 2012; 4(1):178-187.

9. Dubey SP, Lahtinen M, Sillanpää M. Tansy Fruit Mediated Greener Synthesis of Silver and Gold Nanoparticles. Process Biochem, 2010; 45(7):1065-1071.

10. Fazaludeena MF, Manickamb C, Ashankyty IM, Ahmed MQ, Bege QZ. Synthesis and Characterizations of gGold Nanoparticles by Justicia gendarussa Leaf Extract. J. Microbiol. Biotechnol. Res, 2017; 2(1):23-34.

11. Huang J. Biogenic Silver Nanoparticales by Cacumen platycladi Extract: Synthesis, Formation Mechnism, and Antibacterial Activity. Ind. Eng. Chem. Res, 2011;50(15): 9095-9106.

12. Konishi Y, Nomura T, Tsukiyama T, Saitoh N. Microbial Preparation of Gold Nanoparticles by Anaerobic Bacterium. Trans. Mater. Res, 2004; (29):.2341-2343.

13. Kowshik K M, Deshmukh N, Vogel W, Urban J, Kulkarn S K, Paknikar K M. Microbial Synthesis of Semiconductor CdS Nanoparticles, Their Characterization, and Their Use in the Fabrication of an Ideal Diode. Biotechnol. Bioeng, 2002; (78) : 583-584.

14. Li S. Green Synthesis of Silver Nanoparticales using Capsicum annuum L. Extract. Green Chem, 2007; 9(8): 852-858.

15. Maliszewska I, Aniszkiewicz L, Sadowski Z. Biological Synthesis of Gold Nanostructures using the Extract of Trichoderma koningii . Acta Physica Polonica, 2009; (116): 163-165.

16. Mohanpuria P, Rana N K, Yadav S K. Biosynthesis of Nanoparticles: Technological Concepts and Future Applications. Nanopart . Res, 2008; ( 10): 507-517.


17. Mubarakali D, Thajuddin N, Jeganathan K, Gunasekaran M. Plant Extract Mediated Synthesis of Silver and Gold Nanoparticles and Its Antibacterial Activity Against Clinically Isolated Pathogens. Colloids Surf., B, 2011; 85(2):360-365.

18. Nair R. Nanoparticulate Material Delivery to Plants . Plant Sci, 2010; 179(3):154-163

19. Noruzi M, Zare D, Davoodi D. A Rapid Biosynthesis Route for The Preparation of Gold Nanoparticles by Aqueous Extract of Cypress Leaves at Room Temperature. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy,2012; (94): 84-88.

20. Prashant M , Nisha R, Sudesh K. Biosynthesis of Nanoparticles, Technological Concepts and Future Application, Nanoparticle Res, 2007; (21): 507-517.

21. Raghunandan D, Bedre MD, Basavaraja S, Sawle B, Manjunath SY, Venkataraman A. Rapid Biosynthesis of Irregular Shaped Gold Nanoparticles from Macerated Aqueous Extracellular Dried Clove Buds (Syzygium aromaticum) Solution. Colloids Surf., B, 2010; 79(1):235-240.

22. Salari N, Baghizadeh A, Karimimaleh H, Asadi M. Biosynthesis of Gold Nanoparticles by Extract of Aerial Organs of Cumin (Cuminum cyminum L. ). Cellular. Molecular. Res. 2019; 32(3): 286-296.

23. Sarika S. Synthesis, Characterization and Antibacterial Potential of Silver Nanoparticles by Morus nigra Leaf Extract.. Indian J.Pharm. Biol. Res, 2013; 1(4): 16-24.


24. Singaravelu G, Arocklamary S ,Kumar V, Govindaraju K. A Novel Extracellular Synthesis of Monodisperse Gold Nanoparticles using Marine Alga. Colloids Surf., B, 2007; (57): 97-101.

25. Smitha S, Philip D, Gopchandran K. Green Synthesis of Gold Nanoparticles using Cinnamomum zeylanicum Leaf Broth. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2009; 74(3):735-739.

26. Sneha K, Sathishkumar M, Lee SY, Bae MA, Yun YS. Biosynthesis of Au Nanoparticles using Cumin Seed Powder Extract. J. Nanosci. Nanotechnol, 2011;11 (2): 1811-1814.