Effects of Replacing Mineral Selenium Supplement with Selenium Nanoparticles on Blood Parameters of Dairy Calves
Subject Areas : Journal of Animal BiologyMohammad Karimi 1 , mehdi Ganjkhanlou 2 , farhang fatahei 3
1 - Department of Animal Science, Faculty of Agriculture and Natural Resources, University of Tehran, Karaj, Alborz, Iran
2 - Department of Animal Science, Faculty of Agriculture and Natural Resources, University of Tehran, Karaj, Alborz, Iran
3 - Department of Animal Science, Faculty of Agriculture and Natural Resources, University of Tehran, Karaj, Alborz, Iran
Keywords: Nano-selenium, Sodium selenite, Holstein calf, Blood metabolites,
Abstract :
The purpose of this study was to investigate the effects of replacing mineral selenium supplements with nano selenium particles in the feeding of dairy calves and its effects on blood metabolites, and improving the growth performance and skeletal structure of infant calves. The number of 32 newborn Holstein calves with an average body weight of 37.85 ± 4.35 kg in the form of a completely randomized design with 4 treatments (eight calves in each treatment) for 83 days according to the supplemental consumption of milk or drinking water with sources Different selenium were placed. Treatments include: 1) inorganic selenium: providing 0.3 mg of selenium per kilogram of dry matter with sodium selenite, 2) low level of nano selenium: providing 0.15 mg of selenium per kilogram of dry matter with nanoparticles prepared from selenium, 3 (Medium level of nano-selenium: providing 0.3 mg of selenium per kilogram of dry matter with nanoparticles prepared from selenium, 4) High level of nano-selenium: providing 0.45 mg of selenium per kilogram of dry matter with nanoparticles prepared from selenium. The results showed that the calves that received nano selenium had no significant difference in the parameters of aspartate transferase and alanine transaminase compared to sodium selenite. The concentration of glutathione peroxidase in 42 days in nano selenium treatments increased and malondialdehyde decreased linearly significantly compared to mineral selenium (P=0.03). The results of this study showed that nano selenium was effective in improving the antioxidant status of calf blood during post-weaning.
1. AOAC International. 2002. Official Methods of Analysis. 17th ed. AOAC International, Arlington, VA.
2. Arthur J.R., Morrice P.C., Beckett G.J. 1988. Thyroid hormone concentrations in selenium deficient and selenium sufficient cattle. Research in Veterinary Science, 45:122-123.
3. Doucha J., Lívansky´ K., Kotrbácek V., Zachleder V. 2009. Production of Chlorella biomass enriched by selenium and its use in animal nutrition: a review. Applied Microbiology and Biotechnology, 83:1001-1008.
4. Ebrahimi M., Towhidi A., Nikkhah A. 2009. Effect of organic selenium (Sel-Plex) on thermometabolism, blood chemical composition and weight gain in Holstein suckling calves. Asian-Australasian Journal of Animal Sciences, 22:984-992.
5. Ezaki O. 1990. The insulin like effect of selenate in rat adipocytes. Journal of Biological Chemistry, 265:1124-1128.
6. Furnsinn C., Englisch R., Ebner K., Nowotny P., Vogl C., Waldhausl W. 1996. Insulin-like vs. non insulin-like stimulation of glucose metabolism by vanadium, tungsten and selenium compounds in rat muscle. Life Sciences, 59:1989-2000.
7. Goff J.P. 2006. Major advances in our understanding of nutritional influences on bovine health. Journal of Dairy Science, 89:1291-1301.
8. Huang L., Heinloth A.N., Zeng Z.B., Paules R.S., Bushel P.R. 2008. Genes related to apoptosis predict necrosis of the liver as a phenotype observed in rats exposed to a compendium of hepatotoxicants. BMC Genomics, 9:288.
9. Kanani M., Kargar S., Zamiri M.J., Ghoreishi S.M., Mirzaei M. 2019. Reciprocal combinations of alfalfa hay and corn silage in the starter diets of Holstein dairy calves: effects on growth performance, nutrient digestibility, rumen fermentation and selected blood Metabolites. Animal, 13: 2501-2509.
10. Kazemi‐Bonchenari M., Falahati R., Poorhamdollah M., Heidari S.R., Pezeshki A. 2018. Essential oils improved weight gain, growth and feed efficiency of young dairy calves fed 18 or 20 % crude protein starter diets. Journal of Animal Physiology and Animal Nutrition, 102:652-661.
11. Koenig K.M., Beauchemin K.A. 2009. Supplementing selenium yeast to diets with adequate concentrations of selenium: Selenium status, thyroid hormone concentrations and passive transfer of immunoglobulins in dairy cows and calves. Canadian Journal of Animal Science, 89:111-122.
12. Liu Y., Wang C., Liu Q, Guo G., Huo W., Zhang Y., Pei C., Zhang S., Zhang J. 2019. Effects of sodium selenite addition on ruminal fermentation, microflora and urinary excretion of purine derivatives in Holstein dairy bulls. Journal of Animal Physiology and Animal Nutrition, 103:1719-1726.
13. Liu Y., Zhang Z., Dai S., Wang Y., Tian X., Zhao J., Wang C., Liu Q., Guo G., Huo W. 2020. Effects of sodium selenite and coated sodium selenite addition on performance, ruminal fermentation, nutrient digestibility and hepatic gene expression related to lipid metabolism in dairy bulls. Livestock Science, 237:104062.
14. Makizadeh H., Kazemi-Bonchenari M., Mansoori-Yarahmadi H., Fakhraei J., Khanaki H., Drackley J.K., Ghaffari M.H. 2020. Corn-processing and crude protein content in calf starter: effects on growth performance, ruminal fermentation, and blood metabolites. Journal of Dairy Science, 103:9037-9053.
15. McPherson A. 1994. Selenium vitamin E and biological oxidation. In: Cole DJ, Garnsworthy PJ editors. Recent advances in animal nutrition. Oxford: Butterworth and Heinemann’s; p:3-30.
16. Mehdi Y., Dufrasne I. 2016. Selenium in cattle: a review. Molecules, 21:545.
17. Metery G.H., Youssef R.H., Khattab R.M. 1999. Studies on selenium and or vitamin E administration to Egyptian buffalo calves. Mansoura University Journal of Agricultural Sciences, 24:4625-4635.
18. Mohri M., Ehsani A., Norouzian M.A., Bami M.H., Seifi H.A. 2011. Parenteral selenium and vitamin E supplementation to lambs: hematology, serum biochemistry, performance, and relationship with other trace elements. Biological Trace Element Research, 139:308-316.
19. Mohtashami B., Khalilvandi-Behroozyar H., Pirmohammadi R., Dehghan-Banadaky M., Kazemi-Bonchenari M., Dirandeh E., Ghaffari M.H. 2022. The effect of supplemental bioactive fatty acids on growth performance and immune function of milk-fed Holstein dairy calves during heat stress. British Journal of Nutrition, 127:188-201.
20. Qin S., Gao J., Huang K. 2007. Effects of different selenium sources on tissue selenium concentrations, blood GSH-Px activities and plasma interleukin levels in finishing lambs. Biological Trace Element Research, 116:91-102.
21. Rodríguez A.M., Valiente S.L., Brambilla CE, Fernández EL., Maresca S. 2020. Effects of inorganic selenium injection on the performance of beef cows and their subsequent calves. Research in Veterinary Science, 133:117-123.
22. SAS Institute. 2013. SAS User’s Guide. Retrieved on 25 March 2019, from https://support.sas.com/documentation/cdl/en/procstat/66703/PDF/default/procstat.pdf.
23. Shi D., Liao S., Guo S., Li H., Yang M., Tang Z. 2015. Protective effects of selenium on aflatoxin B1-induced mitochondrial permeability transition, DNA damage, and histological alterations in duckling liver. Biological Trace Element Research, 163:162-168.
24. Xu B.H., Xu Z.R., Xia M.S. 2003. Effect of Nano red elemental selenium on GPx activity of broiler chick kidney cells in vitro. Wuhan University Journal of Natural Sciences, 8:1161-1166.
25. Xu Z.Y., Li J., Han J.W. 2007. Effects of se-yeast in dairy ration on somatic cell and anti-oxidation performance. Chinese Journal of Animal Nutrition, 19:753-757.
26. Zhan X., Wang M., Zhao R., Li W., Xu Z. 2007. Effects of different selenium source on selenium distribution, loin quality and antioxidant status in finishing pigs. Animal Feed Science Technology, 132:202-211.
27. Zhang G.W., Wang C., Du H.S., Wu Z.Z., Liu Q., Guo G., Huo W.J., Zhang J., Zhang Y.L., Pei C.X., Zhang S.L. 2020. Effects of folic acid and sodium selenite on growth performance, nutrient digestion, ruminal fermentation and urinary excretion of purine derivatives in Holstein dairy calves. Livestock Science, 231:103884.
28. Zhang J., Wang H., Bao Y., Zhang L. 2004. Nano red elemental selenium has no size effect in the induction of seleno-enzymes in both cultured cells and mice. Life Science, 75:237-244.
29. Zhang J.S., Gao X.Y., Zhang L.D., Bao Y.P. 2001. Biological effects of a Nano red elemental selenium. BioFactors, 15:27-38.
