The Comparison of Serumal Level of Prolactin Between Women with Polycystic Ovarian Syndrome and Control Group

Subject Areas : Journal of Animal Biology

سیدپیمان مقدسی ¹ , غلامحسن واعظی ² , سیدمهدی کلانتر ³

1 - گروه زیست‌شناسی، واحد دامغان، دانشگاه آزاد اسلامی، دامغان، ایران
2 - گروه زیست‌شناسی، واحد دامغان، دانشگاه آزاد اسلامی، دامغان، ایران
3 - واحد ژنتیک، مرکز تحقیقات و درمانی ناباروری، دانشگاه علوم پزشکی شهید صدوقی، یزد، ایران

Received: 2015-08-23 Accepted : 2017-05-21 Published : 2015-07-23

Keywords: PCOs, Serumal level of Prolactin, Hyperandrogenism, Hyperprolactinemia,

Abstract :

Polycystic ovarian syndrome (PCOs) with prevalence between5% to 10% is one of the most common endocrinologic disorders in women during reproductive age. Although, the cause of disease is not completely known, the serum level of some hormones is abnormal. The present study aimed to compare the serumal level of prolactin between women with polycystic ovarian syndrome and control group. This study was conducted during 2012 to 2013 in capital of eight provinces. In total 400 PCOs women and 500 control group were considered. The level of prolactin of serum was measured and the obtained data were analyzed by Mann-Witney test and Spearman correlation coefficient using SPSS software ver. 16.0 and the ROC curves were plotted. The mean serum prolactin level in patients group was 20.08±7.08 ng/ml (10.1- 50.26); while it was 17.08±2.77 ng/ml (12-23) in control group. Significantly higher in patients group (p