The Influence of Drinking Nanosilver on Fetus Death in Rat
Subject Areas : Journal of Animal Biologyوجیهه قربان زاده 1 , عبدالغفار عبادی 2
1 - دانشگاه اصفهان، دانشکده علوم، گروه زیست شناسی، اصفهان، ایران
2 - دانشگاه آزاد اسلامی، واحد جویبار، گروه زیست شناسی، جویبار، ایران
Keywords: Nanosilver, Rat, Cytotoxic effects,
Abstract :
Nanosilver, as one of the wondrous scientific outcomes of nanotechnology, has numerous usages in both medicine and pharmacy. In its larger sizes, silver is a metal with low reaction sensitivity but when transformed to very small particles, as small as nanometer, its special properties are intensified. The purpose of this study is the effect of drinking nanosilver on fetus death in rat. In this investigation, 12 pregnant rats were used in experimental environment. The rats were randomly assigned to 3groups of 4. Group1 or the control group, group2, rats which received high dosages (10ppm) of nanosilver through drinking, group3, rats which received low dosage (1ppm) through the same procedure. From the 16th day of pregnancy on, the pregnant rats were treated with drinking nanosilver with the concentration of 10 and 1ppm and the treatment went on till the 22nd day of pregnancy. Later on, the death rate of the babies was monitored in both the treatment and control groups and result were investiged with SPSS software and one way ANOVA statistics analysis. The results of the study depicted the fact that usage of nanosilver through drinking during pregnancy has cytotoxic effects on fetus and would lead to the death of the baby.