The Effect of Oral Exposing of Lipstick in Lead (Pb) Disposition in kidney
Subject Areas : Journal of Animal Biology
حمید هاشمی مقدم
1
,
عبدالحسین شیروی
2
,
سپیده شاداب
3
,
محبوبه ترابی
4
1 - دانشگاه آزاد اسلامی، واحد دامغان، گروه شیمی، دامغان، ایران
2 - دانشگاه آزاد اسلامی، واحد دامغان، گروه زیست شناسی، دامغان، ایران
3 - دانشگاه آزاد اسلامی، واحد دامغان، گروه زیست شناسی، دامغان، ایران
4 - دانشگاه آزاد اسلامی، واحد دامغان، گروه زیست شناسی، دامغان، ایران
Keywords: Rat, kidney, Lead, Lipstick,
Abstract :
To day use of cosmetics is spread widely by human societies. Information about the health risks that might be associated with lipstick consumption effects is scarce in the literature. The present work investigated the health effects of exposure to lipstick on the disposition of lead (Pb) in kidney of rats. First, Lead contents were determined in 12 different brands of lipsticks using the atomic absorption spectrophotometer coupled to graphite tube atomizer after an acid digestion procedure. Lead was detected in all the studied samples. Then, one brand was selected for feeding to the rats and amount of oral exposing in the three doses was calculated.Sixty rats were used for the experiment. Animals were divided into 4 groups of 15 animals each. While 1group served as control group, the remaining 3 groups were exposed to lipstick through oral gavage for 90 days. Results show that, exposure to the lipstick cause significantly disposition of lead in the kidney of rats and since that study used a dosing regimen similar to 90 days used here, any estimates of kidney concentrations of lead should be revised upward. These might put consumers at the risk of lead poisoning.
