Seroepidemiological study of cytomegalovirus in haemodialysis Patients hospitalized in heamodialysis unit of Jahrom

Subject Areas : Virology

Vahid  Hemayatkhah Jahromi ¹ (Department of Biology, Jahrom Branch, Islamic Azad University, Jahrom, Iran.)
Karamatallah  Dory ² (Department of Microbiology, Jahrom Branch, Islamic Azad University, Jahrom, Iran.)
Hamid Reza  Momeni ³ (Department of Biology, Arak University, Arak, Iran.)
Habiballah  Jowhary ⁴ (Department of Biology, Darab branch, Islamic Azad University, Darab, Iran.)
Hossein  kargar ⁵ (Islamic Azad University, Young Researcher Club, Jahrom, Iran)

Received: 2013-06-21 Accepted : 2013-06-21 Published : 2011-08-01

Keywords: ELISA, IgM, IgG, Cytomegalovirus, Haemodialysis,

Abstract :

 Abstract Background and Objective: Cytomegalovirus leads to severe infection in individuals with immune deficiency and recipient of blood and its production. Infected blood reception,  and haemodialysis are some of the risk factor factors in primary infection of cytomegalovirus. In this case-control study, positive epidemiological of active and passive cytomegalovirus infection were investigated in haemodialysis patients and control group. Material and methods: Blood serums of 43 haemodialysis patients and 43 healthy controls, who were similar to the patients in terms of sex and age, were investigated for determination of specific anti IgG and IgM of cytomegalovirus. Results: Data revealed that 39 haemodialysis patient (69.90%) were positive for anti- IgG CVM and 8 haemodialysis (18.60%) were positive for anti-IgG CMV (active infection with cytomegalovirus) while active infection with cytomegalovirus in control group had significant difference with patient group (36.2%). Conclusion: Cytomegalovirus cause severe infection in haemodialysis patients, and the rate of infection is directly relatd totransfusion repetitions.

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