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Manuscript ID : JMW-2106-1980 (R1) Visit : 219 Page: 6 - 31

10.30495/jmw.2022.1932689.1980

20.1001.1.20083068.1401.15.50.1.3

Article Type: Original Research

International and Iranian leading corona vaccine: classification, structure, efficacy, and side effects

Subject Areas : Microbial Biotechnology

Seyedeh-Masoumeh  Taghizadeh 1 (Biotechnology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran)
Alireza  Ebrahiminezhad 2 (Biotechnology Research Center, Shiraz University of Medical Sciences, Shiraz,, Iran)

Received: 2021-12-12 Accepted : 2022-05-10 Published : 2022-06-05

Keywords: COVID-19, Nucleic acid vaccines, Protein-based vaccines, Viral vaccines, Viral vector vaccines,

Abstract :

Following the global spread of the new coronavirus, extensive international and national efforts were made to develop a vaccine against the virus. Pharmaceutical giants such as Pfizer, Johnssen Biotech, Astrazeneca, Sinovac, Modrena, Biontec, Bharat, Finlay and China National Biotech Group, along with research institutes such as the University of Oxford and the Gamalia Research Center, are examples of companies and centers that were able to be more successful than other competitors in the speed race to make and produce Corona vaccine. In Iran, the attempts to make this vaccine were quickly made and Iranian companies and organizations such as Shafa Pharmed, Imam Khomeini Executive Headquarters, Ministry of Defense, Pasteur Institute and Razi Vaccine and Serum Research Institute are obliged to make efforts in this regard. At present, the corona vaccine produced by these companies and institutions has either received a license or is in the   final stages of clinical studies. Many review articles on these vaccines have been published in    international journals, but just a few articles refer to the efforts made in Iran. Therefore, in the   present article, an attempt has been made to classify and evaluate the structure, efficacy and side effects of these leading international and Iranian coronavirus vaccines. Hence, the information published by the World Health Organization, the US Centers for Disease Control, pharmaceutical companies, reputable research centers and domestic and foreign organizations were employed.  

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